Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lokanath, N.K.; Shiromizu, I.; Ohshima, N.; Nodake, Y.; Sugahara, M.; Yokoyama, S.; Kuramitsu, S.; Miyano, M.; Kunishima, N.
    Structure of aldolase from Thermus thermophilus HB8 showing the contribution of oligomeric state to thermostability (2004), Acta Crystallogr. Sect. D, 60, 1816-1823.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
4.1.2.4 microbatch method, crystal structure of the enzyme and its complex with 2-deoxy-D-ribose 5-phosphate Thermus thermophilus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.2.4 0.056
-
2-deoxy-D-ribose 5-phosphate pH 7.4, 35°C Thermus thermophilus
4.1.2.4 0.075
-
2-deoxy-D-ribose 5-phosphate pH 7.4, 25°C Thermus thermophilus

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.4 Thermus thermophilus
-
HB8
-
4.1.2.4 Thermus thermophilus HB8 / ATCC 27634 / DSM 579
-
HB8
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.2.4 recombinant Thermus thermophilus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.4 2-deoxy-D-ribose 5-phosphate
-
Thermus thermophilus D-glyceraldehyde 3-phosphate + acetaldehyde
-
?
4.1.2.4 2-deoxy-D-ribose 5-phosphate
-
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 D-glyceraldehyde 3-phosphate + acetaldehyde
-
?

Subunits

EC Number Subunits Comment Organism
4.1.2.4 tetramer in the crystal and in solution Thermus thermophilus

Synonyms

EC Number Synonyms Comment Organism
4.1.2.4 TtDERA
-
Thermus thermophilus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
4.1.2.4 5
-
2-deoxy-D-ribose 5-phosphate pH 7.4, 25°C Thermus thermophilus
4.1.2.4 11.4
-
2-deoxy-D-ribose 5-phosphate pH 7.4, 35°C Thermus thermophilus