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Literature summary extracted from

  • Hastings, C.; Rand, T.; Bergen, H.T.; Thliveris, J.A.; Shaw, A.R.; Lombaert, G.A.; Mantsch, H.H.; Giles, B.L.; Dakshinamurti, S.; Scott, J.E.
    Stachybotrys chartarum alters surfactant-related phospholipid synthesis and CTP:cholinephosphate cytidylyltransferase activity in isolated fetal rat type II cells (2005), Toxicol. Sci., 84, 186-194.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.7.15 Lipids regulation of activity by reversible association with membrane lipids Rattus norvegicus
2.7.7.15 phosphatidylglycerol
-
 Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.15 additional information inhibited with spore extract from Stachybotrys chartarum isolated in Cleveland, no effect with extracts from the same organism isolated in Hawaii Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.15 membrane enzyme is activated when bound to vesicles Rattus norvegicus 16020
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.15 CTP + choline phosphate Rattus norvegicus rate limiting enzyme for the synthesis of phosphatidylcholine diphosphate + CDP-choline
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.15 Rattus norvegicus
-
 fetal Sprague-Dawley rats
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.15 lung isolated fetal rat type II cells Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.15 CTP + choline phosphate
-
 Rattus norvegicus diphosphate + CDP-choline
-
 ?
2.7.7.15 CTP + choline phosphate rate limiting enzyme for the synthesis of phosphatidylcholine Rattus norvegicus diphosphate + CDP-choline
-
 ?