EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.4.2.30 | membrane | membrane localization domain | Pseudomonas aeruginosa | 16020 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.2.30 | Pseudomonas aeruginosa | - |
ExoS | - |
2.4.2.30 | Pseudomonas aeruginosa | - |
ExoT | - |
2.4.2.30 | Pseudomonas aeruginosa ExoS | - |
ExoS | - |
2.4.2.30 | Pseudomonas aeruginosa ExoT | - |
ExoT | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.2.30 | NAD+ + (ADP-D-ribosyl)n-acceptor | ExoS has polysubstrate specificity and can ADP-ribosylate numerous host proteins, e.g. monomeric GTPase or vimentin. ExoS also undergoes auto-ADP-ribosylation. Ras has multiple alternative sites for ADP-ribosylation | Pseudomonas aeruginosa | nicotinamide + (ADP-D-ribosyl)n+1-acceptor | - |
? | |
2.4.2.30 | NAD+ + (ADP-D-ribosyl)n-acceptor | ExoT ADP-ribosylates a restricted subset of host proteins including the Crk proteins | Pseudomonas aeruginosa | nicotinamide + (ADP-D-ribosyl)n+1-acceptor | - |
? | |
2.4.2.30 | NAD+ + (ADP-D-ribosyl)n-acceptor | ExoS has polysubstrate specificity and can ADP-ribosylate numerous host proteins, e.g. monomeric GTPase or vimentin. ExoS also undergoes auto-ADP-ribosylation. Ras has multiple alternative sites for ADP-ribosylation | Pseudomonas aeruginosa ExoS | nicotinamide + (ADP-D-ribosyl)n+1-acceptor | - |
? | |
2.4.2.30 | NAD+ + (ADP-D-ribosyl)n-acceptor | ExoT ADP-ribosylates a restricted subset of host proteins including the Crk proteins | Pseudomonas aeruginosa ExoS | nicotinamide + (ADP-D-ribosyl)n+1-acceptor | - |
? | |
2.4.2.30 | NAD+ + (ADP-D-ribosyl)n-acceptor | ExoS has polysubstrate specificity and can ADP-ribosylate numerous host proteins, e.g. monomeric GTPase or vimentin. ExoS also undergoes auto-ADP-ribosylation. Ras has multiple alternative sites for ADP-ribosylation | Pseudomonas aeruginosa ExoT | nicotinamide + (ADP-D-ribosyl)n+1-acceptor | - |
? | |
2.4.2.30 | NAD+ + (ADP-D-ribosyl)n-acceptor | ExoT ADP-ribosylates a restricted subset of host proteins including the Crk proteins | Pseudomonas aeruginosa ExoT | nicotinamide + (ADP-D-ribosyl)n+1-acceptor | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.2.30 | ExoS | bifunctional type-III cytotoxin with an N-terminal RhoGAP domain and and C-terminal ADP-ribosylation domain | Pseudomonas aeruginosa |
2.4.2.30 | ExoT | bifunctional type-III cytotoxin with an N-terminal RhoGAP domain and and C-terminal ADP-ribosylation domain | Pseudomonas aeruginosa |