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Literature summary extracted from

  • Budovskaya, Y.V.; Stephan, J.S.; Deminoff, S.J.; Herman, P.K.
    An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase (2005), Proc. Natl. Acad. Sci. USA, 102, 13933-13938.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.11 cAMP
-
 Saccharomyces cerevisiae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.11 expression of HA-tagged PKA-Atg1345-559 fusion protein in Saccharomyces cerevisiae Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.11 cytoplasm
-
 Saccharomyces cerevisiae 5737
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.11 Mg2+
-
 Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.11 ATP + autophagy-related protein kinase Atg1 Saccharomyces cerevisiae initiating the degradative pathway, PKA regulates the association of Atg1 with the preautophagosomal structure PAS, overview ADP + phosphorylated autophagy-related protein kinase Atg1
-
 ?
2.7.11.11 ATP + autophagy-related protein kinase Atg1 Saccharomyces cerevisiae Y258 initiating the degradative pathway, PKA regulates the association of Atg1 with the preautophagosomal structure PAS, overview ADP + phosphorylated autophagy-related protein kinase Atg1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.11 Saccharomyces cerevisiae
-
-
-
2.7.11.11 Saccharomyces cerevisiae Y258
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.11 ATP + autophagy-related protein kinase Atg1 initiating the degradative pathway, PKA regulates the association of Atg1 with the preautophagosomal structure PAS, overview Saccharomyces cerevisiae ADP + phosphorylated autophagy-related protein kinase Atg1
-
 ?
2.7.11.11 ATP + autophagy-related protein kinase Atg1 phosphorylation at Ser508 and Ser515 Saccharomyces cerevisiae ADP + phosphorylated autophagy-related protein kinase Atg1
-
 ?
2.7.11.11 ATP + autophagy-related protein kinase Atg1 initiating the degradative pathway, PKA regulates the association of Atg1 with the preautophagosomal structure PAS, overview Saccharomyces cerevisiae Y258 ADP + phosphorylated autophagy-related protein kinase Atg1
-
 ?
2.7.11.11 ATP + autophagy-related protein kinase Atg1 phosphorylation at Ser508 and Ser515 Saccharomyces cerevisiae Y258 ADP + phosphorylated autophagy-related protein kinase Atg1
-
 ?
2.7.11.11 additional information potential substrate identification by an evolutionary proteomics approach, overview Saccharomyces cerevisiae ?
-
 ?
2.7.11.11 additional information potential substrate identification by an evolutionary proteomics approach, overview Saccharomyces cerevisiae Y258 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.11 PKA
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.11.11 30
-
 assay at Saccharomyces cerevisiae

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.11 ATP
-
 Saccharomyces cerevisiae