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Literature summary extracted from

  • Wen, B.G.; Pletcher, M.T.; Warashina, M.; Choe, S.H.; Ziaee, N.; Wiltshire, T.; Sauer, K.; Cooke, M.P.
    Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity (2004), Proc. Natl. Acad. Sci. USA, 101, 5604-5609.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.127 ATP + 1D-myo-inositol 1,4,5-trisphosphate Mus musculus
-
 ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
-
 ?
2.7.1.127 ATP + 1D-myo-inositol 1,4,5-trisphosphate Mus musculus C57BL/6
-
 ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
-
 ?
2.7.1.127 additional information Mus musculus isozyme B controls positive selection of T cells and modulates Erk activity, the enzyme is important in Ras signaling which is important for Erk activation, overview ?
-
 ?
2.7.1.127 additional information Mus musculus C57BL/6 isozyme B controls positive selection of T cells and modulates Erk activity, the enzyme is important in Ras signaling which is important for Erk activation, overview ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.127 Mus musculus
-
 C75BL/6 mice
-
2.7.1.127 Mus musculus C57BL/6
-
 C75BL/6 mice
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.127 thymocyte
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.127 ATP + 1D-myo-inositol 1,4,5-trisphosphate
-
 Mus musculus ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
-
 ?
2.7.1.127 ATP + 1D-myo-inositol 1,4,5-trisphosphate
-
 Mus musculus C57BL/6 ADP + 1D-myo-inositol 1,3,4,5-tetrakisphosphate
-
 ?
2.7.1.127 additional information isozyme B controls positive selection of T cells and modulates Erk activity, the enzyme is important in Ras signaling which is important for Erk activation, overview Mus musculus ?
-
 ?
2.7.1.127 additional information isozyme B controls positive selection of T cells and modulates Erk activity, the enzyme is important in Ras signaling which is important for Erk activation, overview Mus musculus C57BL/6 ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.127 inositol (1,4,5) trisphosphate 3 kinase B
-
 Mus musculus
2.7.1.127 Itpkb
-
 Mus musculus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.127 ATP
-
 Mus musculus