EC Number | Application | Comment | Organism |
---|---|---|---|
2.8.2.1 | medicine | concomitant ingestion of beverages such as green tea and black tea may increase the bioavailability of orally administered ritodrine, and perhaps other beta-agonists | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
2.8.2.1 | expression in Escherichia coli, enzyme form SULT1A3 | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.8.2.1 | additional information | enzyme form SULT1A1 is significantly inhibited by all beverages examined (grapefruit juice, orange juice, green tea and black tea) at a concentration of 10%. Green tea and black tea exhibit potent inhibition, even at a concentration of 5%, they both inhibit SULT1A1 by 100%; enzyme form SULT1A3 is significantly inhibited by all beverages examined (grapefruit juice, orange juice, green tea and black tea) at a concentration of 10%. Green tea and black tea exhibit potent inhibition, even at a concentration of 5%, they both inhibit SULT1A3 by more than 95% | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.8.2.1 | 0.438 | - |
ritodrine | enzyme form SULT1A3 | Homo sapiens | |
2.8.2.1 | 3.08 | - |
ritodrine | enzyme form SULT1A1 | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.2.1 | Homo sapiens | - |
enzyme form SULT1A1 | - |
2.8.2.1 | Homo sapiens | - |
enzyme form SULT1A3 | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.8.2.1 | recombinant enzyme, enzyme form SULT1A3 | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.8.2.1 | intestinal mucosa | enzyme form SULT1A1 | Homo sapiens | - |
2.8.2.1 | intestinal mucosa | enzyme form SULT1A3 | Homo sapiens | - |
2.8.2.1 | liver | enzyme form SULT1A1 | Homo sapiens | - |
2.8.2.1 | liver | enzyme form SULT1A3 | Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.2.1 | 3'-phosphoadenylylsulfate + ritodrine | enzyme form SULT1A1 | Homo sapiens | adenosine 3',5'-bisphosphate + ritodrine sulfate | - |
? | |
2.8.2.1 | 3'-phosphoadenylylsulfate + ritodrine | enzyme form SULT1A3 | Homo sapiens | adenosine 3',5'-bisphosphate + ritodrine sulfate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.8.2.1 | SULT1A1 | - |
Homo sapiens |
2.8.2.1 | SULT1A3 | - |
Homo sapiens |