Literature summary extracted from

Taraschenko, O.D.; Barnes, W.G.; Herrick-Davis, K.; Yokoyama, Y.; Boyd, D.L.; Hough, L.B.
Actions of tacrine and galanthamine on histamine-N-methyltransferase (2005), Methods Find. Exp. Clin. Pharmacol., 27, 161-165.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.1.1.8	additional information	not inhibitory: galanthamine up to 0.001 mM	Homo sapiens
2.1.1.8	additional information	not inhibitory: galanthamine up to 0.001 mM	Rattus norvegicus
2.1.1.8	tacrine	50% inhibition at 0.00046 mM for enzyme of embryonic kidney, at 0.0007 mM for recombinant brain enzyme	Homo sapiens
2.1.1.8	tacrine	50% inhibition at 0.00029 mM	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.8	Homo sapiens	-	-	-
2.1.1.8	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.1.8	brain	recombinant enzyme from brain	Homo sapiens	-
2.1.1.8	kidney	-	Rattus norvegicus	-
2.1.1.8	kidney	embryonic cells	Homo sapiens	-

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Release 2023.1 (January 2023)