EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.2.1.3 | Triacsin C | 90% inhibition at 0.02 mM | Mus musculus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.2.1.3 | additional information | Mus musculus | inhibition of ACSL1 activity in adipocytes impairs fatty acid uptake, suggesting that esterification is essential for fatty acid transport. A constitutive interaction between the fatty acid transport protein FATP1 and ACSL1 contributes to efficient cellular uptake of long chain fatty acids in adipocytes through vectorial acylation | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.2.1.3 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.2.1.3 | 3T3-L1 cell | - |
Mus musculus | - |
6.2.1.3 | adipocyte | - |
Mus musculus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.2.1.3 | ATP + oleate + CoA | - |
Mus musculus | AMP + diphosphate + oleoyl-CoA | - |
? | |
6.2.1.3 | additional information | inhibition of ACSL1 activity in adipocytes impairs fatty acid uptake, suggesting that esterification is essential for fatty acid transport. A constitutive interaction between the fatty acid transport protein FATP1 and ACSL1 contributes to efficient cellular uptake of long chain fatty acids in adipocytes through vectorial acylation | Mus musculus | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
6.2.1.3 | More | fatty acid transport protein FATP1 and ACSL1 participate in an oligomeric complex in 3T3-L1 adipocytes. The interaction between ACSL1 and FATP1 is constitutive | Mus musculus |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
6.2.1.3 | ACSL | - |
Mus musculus |
6.2.1.3 | ACSL1 | - |
Mus musculus |
6.2.1.3 | long-chain acyl coenzyme A synthetase 1 | - |
Mus musculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
6.2.1.3 | ATP | - |
Mus musculus |