Literature summary extracted from

Falany, C.N.; Xie, X.; Wheeler, J.B.; Wang, J.; Smith, M.; He, D.; Barnes, S.
Molecular cloning and expression of rat liver bile acid CoA ligase (2002), J. Lipid Res., 43, 2062-2071.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
6.2.1.7	expression of rBAL in Sf9 insect cells	Rattus norvegicus

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
6.2.1.7	Brij-58	-	Rattus norvegicus
6.2.1.7	cholic acid	0.02 mM, 24% inhibition	Rattus norvegicus
6.2.1.7	deoxycholic acid	0.02 mM, 60% inhibition	Rattus norvegicus
6.2.1.7	lithocholic acid	0.02 mM, 96% inhibition	Rattus norvegicus
6.2.1.7	norcholic acid	0.02 mM, 18% inhibition	Rattus norvegicus
6.2.1.7	oleic acid	-	Rattus norvegicus
6.2.1.7	palmitoleic acid	-	Rattus norvegicus
6.2.1.7	trihydroxycoprostanoic acid	0.02 mM, 24% inhibition	Rattus norvegicus
6.2.1.7	Triton X-100	-	Rattus norvegicus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
6.2.1.7	0.032	-	chenodeoxycholate	native recombinant enzyme expressed in Sf9 microsomes	Rattus norvegicus
6.2.1.7	0.064	-	chenodeoxycholate	His-tagged recombinant enzyme	Rattus norvegicus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
6.2.1.7	microsome	-	Rattus norvegicus	-	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.2.1.7	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
6.2.1.7	liver	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.2.1.7	ATP + chenodeoxycholate + CoA	-	Rattus norvegicus	AMP + diphosphate + chenodeoxycholoyl-CoA	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
6.2.1.7	BAL	-	Rattus norvegicus

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Release 2023.1 (January 2023)