Literature summary extracted from

Pereira, C.A.; Alonso, G.D.; Ivaldi, S.; Bouvier, L.A.; Torres, H.N.; Flawia, M.M.
Screening of substrate analogs as potential enzyme inhibitors for the arginine kinase of Trypanosoma cruzi (2003), J. Eukaryot. Microbiol., 50, 132-134.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.3.3	agmatine	10 mM, 79.3% inhibition	Trypanosoma cruzi
2.7.3.3	aminoguanidine	10 mM, 2.6% inhibition	Trypanosoma cruzi
2.7.3.3	canavanine	10 mM, 54.6% inhibition	Trypanosoma cruzi
2.7.3.3	Creatine	10 mM, 12.7% inhibition	Trypanosoma cruzi
2.7.3.3	guanidine butyrate	10 mM, 4.3% inhibition	Trypanosoma cruzi
2.7.3.3	homoarginine	10 mM, 38.2% inhibition	Trypanosoma cruzi
2.7.3.3	L-histidine	10 mM, 2.4% inhibition	Trypanosoma cruzi
2.7.3.3	L-nitroarginine	10 mM, 52.6% inhibition	Trypanosoma cruzi

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.3.3	Trypanosoma cruzi	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.3.3	epimastigote	-	Trypanosoma cruzi	-

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
2.7.3.3	6.02	-	homoarginine	-	Trypanosoma cruzi
2.7.3.3	7.55	-	canavanine	-	Trypanosoma cruzi

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Release 2023.1 (January 2023)