EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.74 | Mg2+ | - |
Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.74 | ATP + 2'-deoxycytidine | Homo sapiens | - |
ADP + 2'-deoxycytidine 5'-phosphate | - |
? | |
2.7.1.74 | ATP + 2-chlorodeoxyadenosine | Homo sapiens | i.e. cladribine | ADP + 2-chlorodeoxyadenosine 5'-phosphate | - |
? | |
2.7.1.74 | additional information | Homo sapiens | the enzyme is active and important in activation of several clinically important deoxynucleoside analogues used for the treatment of haematological and solid malignancies | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.74 | Homo sapiens | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.74 | brain tumor cell | paediatric | Homo sapiens | - |
2.7.1.74 | CCRF-CEM cell | - |
Homo sapiens | - |
2.7.1.74 | HL-60 cell | - |
Homo sapiens | - |
2.7.1.74 | lung cancer cell | adult non-small cell lung cancer | Homo sapiens | - |
2.7.1.74 | additional information | enzyme level in case of acute myeloid leukemia and acute lymphoblastic leukemia in 97 patients, expression levels in different cancer cells, overview | Homo sapiens | - |
2.7.1.74 | retinoblastoma cell | - |
Homo sapiens | - |
2.7.1.74 | U-937 cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.74 | ATP + 2'-deoxycytidine | - |
Homo sapiens | ADP + 2'-deoxycytidine 5'-phosphate | - |
? | |
2.7.1.74 | ATP + 2-chlorodeoxyadenosine | i.e. cladribine | Homo sapiens | ADP + 2-chlorodeoxyadenosine 5'-phosphate | - |
? | |
2.7.1.74 | additional information | the enzyme is active and important in activation of several clinically important deoxynucleoside analogues used for the treatment of haematological and solid malignancies | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.1.74 | dCK | - |
Homo sapiens |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.74 | ATP | - |
Homo sapiens |