EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.8.2.4 | 3',4',7-trihydroxyisoflavone | - |
Homo sapiens | |
2.8.2.4 | daidzein | - |
Homo sapiens | |
2.8.2.4 | daidzein 4,7-bissulfate | IC50: 0.01 mM | Homo sapiens | |
2.8.2.4 | equol | potent mixed type inhibitor | Homo sapiens | |
2.8.2.4 | formononetin | - |
Homo sapiens | |
2.8.2.4 | genistein | potent mixed type inhibitor | Homo sapiens | |
2.8.2.4 | additional information | low SULT1E1 and/or high steroid sulfatase expression in breast tumor tissue correlates with a poor prognosis for disease progression. Concentrations of isoflavonoids that may be achieved in individuals consuming a high-soy diet may inhibit SULT1E1 activity while exerting no effect on steroid sulfatase | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.8.2.4 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.8.2.4 | 3'-phosphoadenylylsulfate + estradiol | - |
Homo sapiens | adenosine 3',5'-bisphosphate + ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.8.2.4 | estrogen sulfotransferase | - |
Homo sapiens |
2.8.2.4 | SULT1E1 | - |
Homo sapiens |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.8.2.4 | 0.0004 | - |
equol | - |
Homo sapiens | |
2.8.2.4 | 0.0005 | - |
genistein | - |
Homo sapiens | |
2.8.2.4 | 0.002 | - |
daidzein | - |
Homo sapiens | |
2.8.2.4 | 0.002 | - |
3',4',7-trihydroxyisoflavone | - |
Homo sapiens | |
2.8.2.4 | 0.006 | - |
formononetin | - |
Homo sapiens |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.8.2.4 | 0.01 | - |
IC50: 0.01 mM | Homo sapiens | daidzein 4,7-bissulfate |