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Literature summary extracted from

  • Cole, S.H.; Carney, G.E.; McClung, C.A.; Willard, S.S.; Taylor, B.J.; Hirsh, J.
    Two functional but noncomplementing Drosophila tyrosine decarboxylase genes: distinct roles for neural tyramine and octopamine in female fertility (2005), J. Biol. Chem., 280, 14948-14955.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.1.25 cloning of tyrosine decarboxylase gene dTdc1 Drosophila melanogaster
4.1.1.25 cloning of tyrosine decarboxylase gene dTdc2 Drosophila melanogaster

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.1.25 L-Tyrosine Drosophila melanogaster flies with a mutation in dTdc2 lack neural tyramine and octopamine and are female sterile due to egg retention. Dtdc2 mutants release eggs into the oviducts but are unable to deposit them Tyramine + CO2
-
?

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.25 Drosophila melanogaster
-
dTdc1
-
4.1.1.25 Drosophila melanogaster
-
dTdc2
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.25 additional information dTdc1 is expressed nonneurally Drosophila melanogaster
-
4.1.1.25 additional information dTdc2 is expressed neurally Drosophila melanogaster
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.25 L-Tyrosine flies with a mutation in dTdc2 lack neural tyramine and octopamine and are female sterile due to egg retention. Dtdc2 mutants release eggs into the oviducts but are unable to deposit them Drosophila melanogaster Tyramine + CO2
-
?

Synonyms

EC Number Synonyms Comment Organism
4.1.1.25 dTdc1
-
Drosophila melanogaster
4.1.1.25 dTdc2
-
Drosophila melanogaster
4.1.1.25 TDC
-
Drosophila melanogaster