Literature summary extracted from

Goodwin, B.L.; Solomonson, L.P.; Eichler, D.C.
Argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells (2004), J. Biol. Chem., 279, 18353-18360.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6.3.4.5	ATP + L-citrulline + L-Asp	Bos taurus	argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells	AMP + diphosphate + L-argininosuccinate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
6.3.4.5	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
6.3.4.5	endothelial cell	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6.3.4.5	ATP + L-citrulline + L-Asp	argininosuccinate synthase expression is required to maintain nitric oxide production and cell viability in aortic endothelial cells	Bos taurus	AMP + diphosphate + L-argininosuccinate	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)