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Literature summary extracted from

  • Ives, E.B.; Nichols, J.; Wente, S.R.; York, J.D.
    Biochemical and functional characterization of inositol 1,3,4,5,6-pentakisphosphate 2-kinases (2000), J. Biol. Chem., 275, 36575-36583.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.158 spIpk1 functionally complements ipk1 mutants of Saccharomyces cerevisiae Schizosaccharomyces pombe

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.158 0.000644
-
 1D-myo-inositol 1,3,4,5,6-pentakisphosphate
-
 Saccharomyces cerevisiae
2.7.1.158 0.0093
-
 ATP
-
 Schizosaccharomyces pombe
2.7.1.158 0.0628
-
 ATP
-
 Saccharomyces cerevisiae
2.7.1.158 0.0628
-
 1D-myo-inositol 1,3,4,5,6-pentakisphosphate
-
 Schizosaccharomyces pombe

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.158 Mg2+ optimal concentration is 10 mM Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.158 Saccharomyces cerevisiae
-
-
-
2.7.1.158 Schizosaccharomyces pombe Q9USK0
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.158 recombinant Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.158 ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate
-
 Saccharomyces cerevisiae ADP + 1D-myo-inositol hexakisphosphate
-
 ?
2.7.1.158 ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate
-
 Schizosaccharomyces pombe ADP + 1D-myo-inositol hexakisphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.158 inositol 1,3,4,5,6-pentakisphosphate 2-kinase
-
 Saccharomyces cerevisiae
2.7.1.158 inositol 1,3,4,5,6-pentakisphosphate 2-kinase
-
 Schizosaccharomyces pombe
2.7.1.158 scIpk1
-
 Saccharomyces cerevisiae
2.7.1.158 spIpk1-C
-
 Schizosaccharomyces pombe

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.158 30
-
-
 Saccharomyces cerevisiae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.158 6.7 7.5
-
 Saccharomyces cerevisiae