Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Buchanan, J.T.; Stannard, J.A.
    Streptococcus iniae phosphoglucomutase is a virulence factor and a target for vaccine developement (2005), Infect. Immun., 73, 6935 - 6944.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
5.4.2.2 drug development the activity of the PGM gene of Streptococcus iniae is linked to a variety of structural and functional phenotypes that translate to dramatically decreased virulence in a model of fish meningoencephalitis Streptococcus iniae

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.4.2.2 expression in Escherichia coli Streptococcus iniae

Organism

EC Number Organism UniProt Comment Textmining
5.4.2.2 Streptococcus iniae
-
-
-
5.4.2.2 Streptococcus iniae K288
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
5.4.2.2 additional information
-
 PGM activity decreases more than fivefold in mutant TnM2 compared to the wild type strain Streptococcus iniae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.2.2 D-glucose-1-phosphate
-
 Streptococcus iniae glucose-6-phosphate
-
 ?
5.4.2.2 D-glucose-1-phosphate
-
 Streptococcus iniae K288 glucose-6-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.4.2.2 PGM
-
 Streptococcus iniae