BRENDA - Enzyme Database

Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2

Inglis-Broadgate, S.L.; Ocaka, L.; Banerjee, R.; Gaasenbeek, M.; Chapple, J.P.; Cheetham, M.E.; Clark, B.J.; Hunt, D.M.; Halford, S.; Gene 356, 19-31 (2005)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
2.7.7.41
expressed in CHO-1 cells; expressed in CHO-1 cells
Mus musculus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
endoplasmic reticulum
associated to the membrane; associated to the membrane
Mus musculus
5783
-
Molecular Weight [Da]
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.7.41
51300
-
x * 51300, calculated from the deduced amino acid sequence
Mus musculus
2.7.7.41
52900
-
x * 52900, calculated from the deduced amino acid sequence
Mus musculus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.7.41
CTP + phosphatidate
Mus musculus
involved in the synthesis of phospholipids and of phosphatidylinositol 4,5-diphosphate, which plays an important role in phosphoinositide-mediated signallng pathways
diphosphate + CDP-diacylglycerol
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.7.41
Mus musculus
P98191
Cds1; Cds1
-
2.7.7.41
Mus musculus
Q99L43
Cds2; Cds2
-
Posttranslational Modification
EC Number
Posttranslational Modification
Commentary
Organism
2.7.7.41
additional information
different potential modification sites predicted from the deduced amino acid sequence; different potential modification sites predicted from the deduced amino acid sequence
Mus musculus
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
brain
-
Mus musculus
-
2.7.7.41
eye
-
Mus musculus
-
2.7.7.41
kidney
weak signal
Mus musculus
-
2.7.7.41
additional information
expressed in all tissues examined
Mus musculus
-
2.7.7.41
retina
expressed in photoreceptors but not in other layers of the retina; ganglion cell layer and inner nuclear layer, not expressed in photoreceptors
Mus musculus
-
2.7.7.41
smooth muscle
-
Mus musculus
-
2.7.7.41
submaxillary gland
weak signal
Mus musculus
-
2.7.7.41
testis
-
Mus musculus
-
2.7.7.41
thyroid gland
weak signal
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + phosphatidate
-
661820
Mus musculus
diphosphate + CDP-diacylglycerol
-
-
-
?
2.7.7.41
CTP + phosphatidate
involved in the synthesis of phospholipids and of phosphatidylinositol 4,5-diphosphate, which plays an important role in phosphoinositide-mediated signallng pathways
661820
Mus musculus
diphosphate + CDP-diacylglycerol
-
-
-
?
Subunits
EC Number
Subunits
Commentary
Organism
2.7.7.41
?
x * 51300, calculated from the deduced amino acid sequence; x * 52900, calculated from the deduced amino acid sequence
Mus musculus
pI Value
EC Number
Organism
Commentary
pI Value Maximum
pI Value
2.7.7.41
Mus musculus
calculated from the deduced amino acid sequence
-
6.6
2.7.7.41
Mus musculus
calculated from the deduced amino acid sequence
-
7.62
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
2.7.7.41
expressed in CHO-1 cells
Mus musculus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.7.41
endoplasmic reticulum
associated to the membrane
Mus musculus
5783
-
Molecular Weight [Da] (protein specific)
EC Number
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
2.7.7.41
51300
-
x * 51300, calculated from the deduced amino acid sequence
Mus musculus
2.7.7.41
52900
-
x * 52900, calculated from the deduced amino acid sequence
Mus musculus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.7.41
CTP + phosphatidate
Mus musculus
involved in the synthesis of phospholipids and of phosphatidylinositol 4,5-diphosphate, which plays an important role in phosphoinositide-mediated signallng pathways
diphosphate + CDP-diacylglycerol
-
-
?
Posttranslational Modification (protein specific)
EC Number
Posttranslational Modification
Commentary
Organism
2.7.7.41
additional information
different potential modification sites predicted from the deduced amino acid sequence
Mus musculus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.7.41
brain
-
Mus musculus
-
2.7.7.41
eye
-
Mus musculus
-
2.7.7.41
kidney
weak signal
Mus musculus
-
2.7.7.41
additional information
expressed in all tissues examined
Mus musculus
-
2.7.7.41
retina
expressed in photoreceptors but not in other layers of the retina
Mus musculus
-
2.7.7.41
retina
ganglion cell layer and inner nuclear layer, not expressed in photoreceptors
Mus musculus
-
2.7.7.41
smooth muscle
-
Mus musculus
-
2.7.7.41
submaxillary gland
weak signal
Mus musculus
-
2.7.7.41
testis
-
Mus musculus
-
2.7.7.41
thyroid gland
weak signal
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.7.41
CTP + phosphatidate
-
661820
Mus musculus
diphosphate + CDP-diacylglycerol
-
-
-
?
2.7.7.41
CTP + phosphatidate
involved in the synthesis of phospholipids and of phosphatidylinositol 4,5-diphosphate, which plays an important role in phosphoinositide-mediated signallng pathways
661820
Mus musculus
diphosphate + CDP-diacylglycerol
-
-
-
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
2.7.7.41
?
x * 52900, calculated from the deduced amino acid sequence
Mus musculus
2.7.7.41
?
x * 51300, calculated from the deduced amino acid sequence
Mus musculus
pI Value (protein specific)
EC Number
Organism
Commentary
pI Value Maximum
pI Value
2.7.7.41
Mus musculus
calculated from the deduced amino acid sequence
-
6.6
2.7.7.41
Mus musculus
calculated from the deduced amino acid sequence
-
7.62