Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Samsonova, N.N.; Smirnov, S.V.; Novikova, A.E.; Ptitsyn, L.R.
    Identification of Escherichia coli K12 YdcW protein as a gamma-aminobutyraldehyde dehydrogenase (2005), FEBS Lett., 579, 4107-4112.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.19 0.041
-
 4-Aminobutyraldehyde 0.1 M Tris-HCl pH 7.5, 1 mM NAD+, 25°C Escherichia coli
1.2.1.19 0.196
-
 Butyraldehyde 0.1 M Tris-HCl pH 7.5, 1 mM NAD+, 25°C Escherichia coli

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
1.2.1.19 51000
-
 single subunit, SDS-PAGE Escherichia coli
1.2.1.19 202000
-
 native protein, gel-filtration Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.19 Escherichia coli P77674
-
-
1.2.1.19 Escherichia coli K12 MG1655 P77674
-
-
2.6.1.82 Escherichia coli
-
 K12 strain
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.2.1.19 to homogeneity by ammonium sulfate precipitation, anion-exchange chromatography and hydrophobic interaction chromatography Escherichia coli
2.6.1.82
-
 Escherichia coli

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.19 cell culture
-
 Escherichia coli
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.19 4-aminobutyraldehyde + NAD+ + H2O
-
 Escherichia coli 4-aminobutanoate + NADH
-
 ?
1.2.1.19 4-aminobutyraldehyde + NAD+ + H2O
-
 Escherichia coli K12 MG1655 4-aminobutanoate + NADH
-
 ?
1.2.1.19 4-aminobutyraldehyde + NADP+ + H2O
-
 Escherichia coli 4-aminobutanoate + NADPH
-
 ?
1.2.1.19 4-aminobutyraldehyde + NADP+ + H2O
-
 Escherichia coli K12 MG1655 4-aminobutanoate + NADPH
-
 ?
1.2.1.19 butyraldehyde + NAD+ + H2O
-
 Escherichia coli butyrate + NADH + H+
-
 ?
1.2.1.19 butyraldehyde + NAD+ + H2O
-
 Escherichia coli K12 MG1655 butyrate + NADH + H+
-
 ?
2.6.1.82 putrescine + 2-oxoglutarate coupling action of Escherichia coli YgjG putrescine transaminase and YdcW dehydrogenase Escherichia coli L-glutamate + 4-aminobutanal
-
 ?

Subunits

EC Number Subunits Comment Organism
1.2.1.19 tetramer 4 * 51000 Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
1.2.1.19 ABALDH
-
 Escherichia coli
1.2.1.19 gamma-aminobutyraldehyde dehydrogenase
-
 Escherichia coli
1.2.1.19 YdcW
-
 Escherichia coli
2.6.1.82 putrescine transaminase
-
 Escherichia coli
2.6.1.82 YgjG
-
 Escherichia coli

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
1.2.1.19 0.3
-
 Butyraldehyde 0.1 M Tris-HCl pH 7.5, 1 mM NAD+, 25°C Escherichia coli
1.2.1.19 7.7
-
 4-Aminobutyraldehyde 0.1 M Tris-HCl pH 7.5, 1 mM NAD+, 25°C Escherichia coli