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Literature summary extracted from

  • Granero, F.; Revert, F.; Revert-Ros, F.; Lainez, S.; Martinez-Martinez, P.; Saus, J.
    A human-specific TNF-responsive promoter for Goodpasture antigen-binding protein (2005), FEBS J., 272, 5291-5305.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.9 additional information expression of the Goodpasture antigen-binding protein is induced by tumor necrosis factor Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.9 DNA sequence determination and analysis, a TNF-responsive transcription unit that locates the enzyme in the signalling cascade of TNF, regulation of transcription, e.g. by tumor necrosis factor, via cooperation in a bidirectional transcription complex with the gene encoding the DNA polymerase kappa, NFkappaB, and a 140-bp promoter with a Sp1 site and a TATA-like element, promoter analysis, overview Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.9 ATP + [Goodpasture antigen-binding protein] Homo sapiens autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen, the enzyme is involved in autoimmune processes and disease ADP + [Goodpasture antigen-binding phosphoprotein]
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.9 Homo sapiens Q9Y5P4
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.9 HEK-293 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.9 ATP + [Goodpasture antigen-binding protein] autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen, the enzyme is involved in autoimmune processes and disease Homo sapiens ADP + [Goodpasture antigen-binding phosphoprotein]
-
 ?
2.7.11.9 ATP + [Goodpasture antigen-binding protein] autophosphorylation via the enzyme's serine/threonine kinase activity that specifically targets a motif in the NC1 domain of the alpha3 chain of type IV collagen, the Good pasture autoantigen Homo sapiens ADP + [Goodpasture antigen-binding phosphoprotein]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.11.9 goodpasture-antigen-binding protein kinase
-
 Homo sapiens
2.7.11.9 GPBP
-
 Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.9 ATP
-
 Homo sapiens