EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.11.18 | expression of GFP-tagged enzyme in HeLa cells | Homo sapiens |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.18 | Ca2+ | dependent on | Homo sapiens | |
2.7.11.18 | Ca2+ | dependent on | Oryctolagus cuniculus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.11.18 | 108000 | 125000 | short myosin light chain kinase | Oryctolagus cuniculus |
2.7.11.18 | 210000 | - |
long myosin light chain kinase | Homo sapiens |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.18 | ATP + [myosin light chain] | Homo sapiens | - |
ADP + [myosin light chain] phosphate | - |
? | |
2.7.11.18 | ATP + [myosin light chain] | Oryctolagus cuniculus | - |
ADP + [myosin light chain] phosphate | - |
? | |
2.7.11.18 | additional information | Homo sapiens | the enzyme activity is cell cycle regulated with a decrease in activity during mitosis due to phosphorylation, inhibition of enzyme phosphorylation during mitosis leads to microtubule defects, overview | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.11.18 | Homo sapiens | - |
- |
- |
2.7.11.18 | Oryctolagus cuniculus | - |
short enzyme form | - |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
2.7.11.18 | phosphoprotein | diffential phosphorylation by Aurora B on serine residues during interphase and mitosis has regulatory function, phosphorylation sites for Aurora B on the enzyme, overview | Oryctolagus cuniculus |
2.7.11.18 | phosphoprotein | diffential phosphorylation by Aurora B on serine residues, e.g. in the enzyme's IgG domain, during interphase and mitosis has regulatory function, phosphorylation sites for Aurora B on the enzyme, overview | Homo sapiens |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.11.18 | recombinant GFP-fusion enzyme from HeLa cells | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.11.18 | HeLa cell | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.11.18 | ATP + [myosin light chain] | - |
Homo sapiens | ADP + [myosin light chain] phosphate | - |
? | |
2.7.11.18 | ATP + [myosin light chain] | - |
Oryctolagus cuniculus | ADP + [myosin light chain] phosphate | - |
? | |
2.7.11.18 | additional information | the enzyme activity is cell cycle regulated with a decrease in activity during mitosis due to phosphorylation, inhibition of enzyme phosphorylation during mitosis leads to microtubule defects, overview | Homo sapiens | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.11.18 | long myosin light chain kinase | - |
Homo sapiens |
2.7.11.18 | short myosin light chain kinase | - |
Oryctolagus cuniculus |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.7.11.18 | ATP | - |
Homo sapiens | |
2.7.11.18 | ATP | - |
Oryctolagus cuniculus | |
2.7.11.18 | Calmodulin | dependent on | Homo sapiens | |
2.7.11.18 | Calmodulin | dependent on | Oryctolagus cuniculus |