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Literature summary extracted from

  • Niittymaki, J.; Mattila, P.; Roos, C.; Huopaniemi, L.; Sjoblom, S.; Renkonen, R.
    Cloning and expression of murine enzymes involved in the salvage pathway of GDP-L-fucose (2004), Eur. J. Biochem., 271, 78-86.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.52 two different transcripts of 3057 and 3270 base pairs expressed in COS-7 cells, only the longer splice variant is enzymatically active Mus musculus
2.7.7.30
-
 Mus musculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.52 111000
-
 short splicing variant Mus musculus
2.7.1.52 120000
-
 long splicing variant Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.52 ATP + L-fucose Mus musculus involved in GDP-L-fucose salvage pathway ADP + beta-L-fucose 1-phosphate
-
 ?
2.7.7.30 GTP + L-fucose 1-phosphate Mus musculus the enzyme is involved in the salvage pathway of GDP-L-fucose diphosphate + GDP-L-fucose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.52 Mus musculus Q7TMC8 long splicing variant
-
2.7.1.52 Mus musculus Q7TS31 short, inactive splicing variant
-
2.7.7.30 Mus musculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.52 brain
-
 Mus musculus
-
2.7.1.52 heart
-
 Mus musculus
-
2.7.1.52 kidney
-
 Mus musculus
-
2.7.1.52 liver
-
 Mus musculus
-
2.7.1.52 lung
-
 Mus musculus
-
2.7.1.52 ovary
-
 Mus musculus
-
2.7.1.52 spleen
-
 Mus musculus
-
2.7.1.52 testis
-
 Mus musculus
-
2.7.7.30 brain high expression level Mus musculus
-
2.7.7.30 heart low expression level Mus musculus
-
2.7.7.30 kidney high expression level Mus musculus
-
2.7.7.30 liver low expression level Mus musculus
-
2.7.7.30 lung low expression level Mus musculus
-
2.7.7.30 ovary high expression level Mus musculus
-
2.7.7.30 spleen low expression level Mus musculus
-
2.7.7.30 testis high expression level Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.52 ATP + L-fucose
-
 Mus musculus ADP + beta-L-fucose 1-phosphate
-
 ?
2.7.1.52 ATP + L-fucose involved in GDP-L-fucose salvage pathway Mus musculus ADP + beta-L-fucose 1-phosphate
-
 ?
2.7.7.30 GTP + L-fucose 1-phosphate the enzyme is involved in the salvage pathway of GDP-L-fucose Mus musculus diphosphate + GDP-L-fucose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.52 ATP:6-deoxy-beta-L-galactose 1-phosphotransferase
-
 Mus musculus
2.7.1.52 More two splicing variants with slightly different molecular weights, only long variant was found to be active Mus musculus
2.7.7.30 GDP-L-fucose pyrophosphorylase
-
 Mus musculus