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Literature summary extracted from

  • Brandenburg, K.; Garidel, P.; Schromm, A.B.; Andra, J.; Kramer, A.; Egmond, M.; Wiese, A.
    Investigation into the interaction of the bacterial protease OmpT with outer membrane lipids and biological activity of OmpT:lipopolysaccharide complexes (2005), Eur. Biophys. J., 34, 28-41.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.23.49 lipopolysaccharides e.g. LPS K12, required for activity, lipid-protein interactions, complex activity analysis on model membranes and human mononuclear cells, overview Escherichia coli
3.4.23.49 Phospholipids lipid-protein interactions Escherichia coli

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.23.49 recombinant expression of OmpT in inclusion bodies Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.23.49 outer membrane enzyme incorporation mechanism into membranes, overview Escherichia coli 19867
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.23.49 additional information Escherichia coli the enzyme is involved in cell defense and induced production of TNFalpha, especially in clinical isolates, the enzyme is not stimulated by toll-like receptors 2 and 4 signalling ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.23.49 Escherichia coli
-
-
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.23.49 additional information
-
enzyme-LPS activity in endotoxin units Escherichia coli

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.23.49 additional information the enzyme is involved in cell defense and induced production of TNFalpha, especially in clinical isolates, the enzyme is not stimulated by toll-like receptors 2 and 4 signalling Escherichia coli ?
-
?
3.4.23.49 additional information protein-lipid interactions on model membranes and human mononuclear cells, overview Escherichia coli ?
-
?

Subunits

EC Number Subunits Comment Organism
3.4.23.49 More enzyme secondary structure analysis Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
3.4.23.49 ompT
-
Escherichia coli