Literature summary extracted from

Xie, P.; Liu, M.L.; Gu, Y.P.; Lu, J.; Xu, X.; Zeng, W.M.; Song, H.P.
Oestrogen improves glucose metabolism and insulin signal transduction in HepG2 cells (2003), Clin. Exp. Pharmacol. Physiol., 30, 643-648.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.7.1.11	additional information	addition of oestradiol increases enzyme activity in intact cells	Homo sapiens

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.7.1.11	additional information	high insulin concentration decreases enzyme activity in intact cells	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.1.11	ATP + D-fructose 1-phosphate	Homo sapiens	key enzyme of glucose metabolism	ADP + D-fructose 1,6-bisphosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.11	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.11	Hep-G2 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.11	ATP + D-fructose 1-phosphate	-	Homo sapiens	ADP + D-fructose 1,6-bisphosphate	-	?
2.7.1.11	ATP + D-fructose 1-phosphate	key enzyme of glucose metabolism	Homo sapiens	ADP + D-fructose 1,6-bisphosphate	-	?

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Release 2023.1 (January 2023)