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Literature summary extracted from

  • Fischbach, M.A.; Settleman, J.
    Specific biochemical inactivation of oncogenic Ras proteins by nucleoside diphosphate kinase (2003), Cancer Res., 63, 4089-4094.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.4.6 expression of GST-fusion NM23 protein in Escherichia coli Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.4.6 15000
-
 x * 15000, SDS-PAGE Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.4.6 ATP + NDP Escherichia coli contributes to the maintenance of the cellular pools of all nucleosides triphosphates ADP + NTP
-
 ?
2.7.4.6 ATP + NDP Homo sapiens contributes to the maintenance of the cellular pools of all nucleosides triphosphates, NM23 metastasis suppressor involved in inactivation of oncogenic forms of Ras proteins ADP + NTP
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.4.6 Escherichia coli
-
-
-
2.7.4.6 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.4.6
-
 Escherichia coli
2.7.4.6
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.4.6 ATP + NDP
-
 Escherichia coli ADP + NTP
-
 ?
2.7.4.6 ATP + NDP
-
 Homo sapiens ADP + NTP
-
 ?
2.7.4.6 ATP + NDP contributes to the maintenance of the cellular pools of all nucleosides triphosphates Escherichia coli ADP + NTP
-
 ?
2.7.4.6 ATP + NDP contributes to the maintenance of the cellular pools of all nucleosides triphosphates, NM23 metastasis suppressor involved in inactivation of oncogenic forms of Ras proteins Homo sapiens ADP + NTP
-
 ?
2.7.4.6 GTP-bound Ras protein + NDP in vitro, inactivation of mutant oncogenic Ras proteins Escherichia coli GDP-bound Ras protein + NTP
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.4.6 ? x * 15000, SDS-PAGE Escherichia coli

Synonyms

EC Number Synonyms Comment Organism
2.7.4.6 NDK
-
 Homo sapiens
2.7.4.6 NM23 metastasis suppressor exhibits Ndk activity Homo sapiens