Literature summary extracted from

Dunlop, D.S.; Neidle, A.
Regulation of serine racemase activity by amino acids (2005), Brain Res. Mol. Brain Res., 133, 208-214.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
5.1.1.18	beta-chloro-L-alanine	2 mM, 68% residual activity	Mus musculus
5.1.1.18	beta-fluoro-D,L-alanine	2 mM, 81% residual activity	Mus musculus
5.1.1.18	D-cysteine	2 mM, 72% residual activity	Mus musculus
5.1.1.18	glycine	2 mM, 20% residual activity	Mus musculus
5.1.1.18	L-2,3-diaminopropionic acid	2 mM, 68% residual activity	Mus musculus
5.1.1.18	L-asparagine	2 mM, 38% residual activity	Mus musculus
5.1.1.18	L-aspartic acid	2 mM, 53% residual activity	Mus musculus
5.1.1.18	L-cysteine	2 mM, 58% residual activity	Mus musculus
5.1.1.18	L-homocysteic acid	2 mM, 59% residual activity	Mus musculus
5.1.1.18	L-serine-O-sulfate	2 mM, 9% residual activity	Mus musculus
5.1.1.18	oxaloacetic acid	2 mM, 56% residual activity	Mus musculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
5.1.1.18	Mus musculus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
5.1.1.18	brain	-	Mus musculus	-

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
5.1.1.18	1.9	-	L-aspartic acid	pH 8.6, 37°C	Mus musculus

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Release 2023.1 (January 2023)