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Literature summary extracted from

  • Feksa, L.R.; Cornelio, A.R.; Dutra-Filho, C.S.; de Souza Wyse, A.T.; Wajner, M.; Wannmacher, C.M.
    Characterization of the inhibition of pyruvate kinase caused by phenylalanine and phenylpyruvate in rat brain cortex (2003), Brain Res., 968, 199-205.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.40 Phe competitive with ADP and phosphoenolpyruvate, Ala prevents inhibition Rattus norvegicus
2.7.1.40 phenylpyruvate competitive with ADP and phosphoenolpyruvate, Ala prevents inhibition Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.40 ADP + phosphoenolpyruvate Rattus norvegicus the enzyme catalyzes an important regulatory step in the glycolysis pathway, the main route that provides energy for brain function ATP + pyruvate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.40 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.40 brain
-
 Rattus norvegicus
-
2.7.1.40 cerebral cortex
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.40 ADP + phosphoenolpyruvate
-
 Rattus norvegicus ATP + pyruvate
-
 ?
2.7.1.40 ADP + phosphoenolpyruvate the enzyme catalyzes an important regulatory step in the glycolysis pathway, the main route that provides energy for brain function Rattus norvegicus ATP + pyruvate
-
 ?