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Literature summary extracted from

  • Lamarche, B.J.; Showalter, A.K.; Tsai, M.D.
    An error-prone viral DNA ligase (2005), Biochemistry, 44, 8408-8417.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
6.5.1.1
-
 Tequatrovirus T4
6.5.1.1
-
 African swine fever virus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.5.1.1 additional information
-
 additional information KM-values as a function of 3'-base pair identity Tequatrovirus T4
6.5.1.1 additional information
-
 additional information KM-values as a function of 3'-base pair identity African swine fever virus

Organism

EC Number Organism UniProt Comment Textmining
6.5.1.1 African swine fever virus
-
-
-
6.5.1.1 Tequatrovirus T4
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.5.1.1
-
 Tequatrovirus T4
6.5.1.1
-
 African swine fever virus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.5.1.1 ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m
-
 Tequatrovirus T4 AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?
6.5.1.1 ATP + (deoxyribonucleotide)n + (deoxyribonucleotide)m DNA ligase of Africxan swine fever virus is the lowest-fidelity DNA ligase ever reported, capable of ligating a 3' C:T mismatched nick (where C and T are the templating and nascent nucleotides, respectively) more efficient than nicks containing Watson-Crick base pairs. The DNA ligase of African swine fever virus adenylates the 3'-amino-containing substrate extremely inefficiently, with reactions typically proceeding to only 5% completion African swine fever virus AMP + diphosphate + (deoxyribonucleotide)m+n
-
 ?

Synonyms

EC Number Synonyms Comment Organism
6.5.1.1 DNA ligase
-
 Tequatrovirus T4
6.5.1.1 DNA ligase
-
 African swine fever virus

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
6.5.1.1 additional information
-
 additional information turnover numbers as a function of 3'-base pair identity Tequatrovirus T4
6.5.1.1 additional information
-
 additional information turnover numbers as a function of 3'-base pair identity African swine fever virus