EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.7.7.30 | D184A | the ratio of turnover number to Km-value (for GTP) is 1.02fold higher than the wild-type ratio | Homo sapiens |
2.7.7.30 | D299A | the ratio of turnover number to Km-value (for GTP) is 1.04fold higher than the wild-type ratio | Homo sapiens |
2.7.7.30 | D427A | the ratio of turnover number to Km-value (for GTP) is 1.06fold lower than the wild-type ratio | Homo sapiens |
2.7.7.30 | D77A | the ratio of turnover number to Km-value (for GTP) is 16600fold lower than the wild-type ratio | Homo sapiens |
2.7.7.30 | E289A | the ratio of turnover number to Km-value (for GTP) is 1.1fold lower than the wild-type ratio | Homo sapiens |
2.7.7.30 | E297A | the ratio of turnover number to Km-value (for GTP) is 19.5fold lower than the wild-type ratio | Homo sapiens |
2.7.7.30 | E297A/E432A | the ratio of turnover number to Km-value (for GTP) is 24900fold lower than the wild-type ratio | Homo sapiens |
2.7.7.30 | E432A | the ratio of turnover number to Km-value (for GTP) is 113fold lower than the wild-type ratio | Homo sapiens |
2.7.7.30 | E566A | the ratio of turnover number to Km-value (for GTP) is 1.06fold higher than the wild-type ratio | Homo sapiens |
2.7.7.30 | E574A | the ratio of turnover number to Km-value (for GTP) is 1.05fold lower than the wild-type ratio | Homo sapiens |
2.7.7.30 | K478A | the ratio of turnover number to Km-value (for GTP) is 1.13fold lower than the wild-type ratio | Homo sapiens |
2.7.7.30 | K479A | the ratio of turnover number to Km-value (for GTP) is 1.15fold lower than the wild-type ratio | Homo sapiens |
2.7.7.30 | K482A | the ratio of turnover number to Km-value (for GTP) is 166fold lower than the wild-type ratio | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.7.30 | 0.0491 | - |
GTP | pH 7.0, 37°C, mutant enzyme D427A | Homo sapiens | |
2.7.7.30 | 0.0496 | - |
GTP | pH 7.0, 37°C, mutant enzyme E566A | Homo sapiens | |
2.7.7.30 | 0.0501 | - |
GTP | pH 7.0, 37°C, mutant enzyme D299A | Homo sapiens | |
2.7.7.30 | 0.0502 | - |
GTP | pH 7.0, 37°C, wild-type enzyme | Homo sapiens | |
2.7.7.30 | 0.0506 | - |
GTP | pH 7.0, 37°C, mutant enzyme E574A | Homo sapiens | |
2.7.7.30 | 0.0511 | - |
GTP | pH 7.0, 37°C, mutant enzyme K479A | Homo sapiens | |
2.7.7.30 | 0.0512 | - |
GTP | pH 7.0, 37°C, mutant enzyme D184A | Homo sapiens | |
2.7.7.30 | 0.0522 | - |
GTP | pH 7.0, 37°C, mutant enzyme K478A | Homo sapiens | |
2.7.7.30 | 0.0537 | - |
GTP | pH 7.0, 37°C, mutant enzyme E289A | Homo sapiens | |
2.7.7.30 | 0.0805 | - |
GTP | pH 7.0, 37°C, mutant enzyme E297A | Homo sapiens | |
2.7.7.30 | 0.127 | - |
GTP | pH 7.0, 37°C, mutant enzyme E432A | Homo sapiens | |
2.7.7.30 | 0.289 | - |
GTP | pH 7.0, 37°C, mutant enzyme D77A | Homo sapiens | |
2.7.7.30 | 0.422 | - |
GTP | pH 7.0, 37°C, mutant enzyme E297A/E432A | Homo sapiens | |
2.7.7.30 | 0.633 | - |
GTP | pH 7.0, 37°C, mutant enzyme K482A | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.7.30 | Homo sapiens | - |
- |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.7.30 | GTP + L-fucose 1-phosphate | - |
Homo sapiens | diphosphate + GDP-L-fucose | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.7.7.30 | GFPP | - |
Homo sapiens |
2.7.7.30 | GTP fucose pyrophosphorylase | - |
Homo sapiens |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.7.30 | 0.001 | - |
GTP | pH 7.0, 37°C, mutant enzyme D77A | Homo sapiens | |
2.7.7.30 | 0.001 | - |
GTP | pH 7.0, 37°C, mutant enzyme E297A/E432A | Homo sapiens | |
2.7.7.30 | 0.05 | - |
GTP | pH 7.0, 37°C, mutant enzyme E432A | Homo sapiens | |
2.7.7.30 | 0.19 | - |
GTP | pH 7.0, 37°C, mutant enzyme K482A | Homo sapiens | |
2.7.7.30 | 0.2 | - |
GTP | pH 7.0, 37°C, mutant enzyme E297A | Homo sapiens | |
2.7.7.30 | 2.2 | - |
GTP | pH 7.0, 37°C, mutant enzyme K479A | Homo sapiens | |
2.7.7.30 | 2.3 | - |
GTP | pH 7.0, 37°C, mutant enzyme K478A | Homo sapiens | |
2.7.7.30 | 2.4 | - |
GTP | pH 7.0, 37°C, mutant enzyme E289A | Homo sapiens | |
2.7.7.30 | 2.4 | - |
GTP | pH 7.0, 37°C, mutant enzyme E574A | Homo sapiens | |
2.7.7.30 | 2.5 | - |
GTP | pH 7.0, 37°C, wild-type enzyme | Homo sapiens | |
2.7.7.30 | 2.6 | - |
GTP | pH 7.0, 37°C, mutant enzyme D184A | Homo sapiens | |
2.7.7.30 | 2.6 | - |
GTP | pH 7.0, 37°C, mutant enzyme D299A | Homo sapiens | |
2.7.7.30 | 2.6 | - |
GTP | pH 7.0, 37°C, mutant enzyme D427A | Homo sapiens | |
2.7.7.30 | 2.6 | - |
GTP | pH 7.0, 37°C, mutant enzyme E566A | Homo sapiens |