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Literature summary extracted from

  • Rylova, S.N.; Albertioni, F.; Flygh, G.; Eriksson, S.
    Activity profiles of deoxynucleoside kinases and 5'-nucleotidases in cultured adipocytes and myoblastic cells: insights into mitochondrial toxicity of nucleoside analogs (2005), Biochem. Pharmacol., 69, 951-960.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.74 quantitative real-time-PCR Homo sapiens
2.7.1.113 quantitative real-time-PCR Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.74 cytosol
-
 Homo sapiens 5829
-
2.7.1.113 mitochondrion
-
 Homo sapiens 5739
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.74 Mg2+
-
 Homo sapiens
2.7.1.113 Mg2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.113 ATP + 2'-deoxyguanosine Homo sapiens
-
 ADP + 2'-deoxyguanosine 5'-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.74 Homo sapiens
-
-
-
2.7.1.113 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.74 adipocyte
-
 Homo sapiens
-
2.7.1.74 CEM cell proliferating lymphocyte Homo sapiens
-
2.7.1.74 lymphocyte
-
 Homo sapiens
-
2.7.1.113 adipocyte
-
 Homo sapiens
-
2.7.1.113 CEM cell proliferating lymphocyte Homo sapiens
-
2.7.1.113 lymphocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.1.74 0.0000057
-
 differentiated adipocytes Homo sapiens
2.7.1.74 0.0000521
-
 CEM lymphocytes Homo sapiens
2.7.1.113 0.0000032
-
 CEM lymphocytes Homo sapiens
2.7.1.113 0.0000635
-
 differentiated adipocytes Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.74 ATP + 2'-deoxycytidine
-
 Homo sapiens ADP + 2'-deoxycytidine 5'-phosphate
-
 ?
2.7.1.113 ATP + 2'-deoxyguanosine
-
 Homo sapiens ADP + 2'-deoxyguanosine 5'-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.74 dCK
-
 Homo sapiens
2.7.1.113 DGK
-
 Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.74 7.6
-
 assay at Homo sapiens
2.7.1.113 7.6
-
 assay at Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.74 ATP
-
 Homo sapiens
2.7.1.113 ATP
-
 Homo sapiens