Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Kang, S.; Song, J.; Kang, J.; Kang, H.; Lee, D.; Lee, Y.; Park, D.
    Suppression of the alpha-isoform of class II phosphoinositide 3-kinase gene expression leads to apoptotic cell death (2005), Biochem. Biophys. Res. Commun., 329, 6-10.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.154 growth factors addition of serum to growth-factor-deficient medium increases PI3K-C2alpha expression Homo sapiens
2.7.1.154 Insulin
-
Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.154 suppression of expression of recombinant alpha-isoform of class II PI3K and endogenous enzyme in transfected CHO-R1 cells by expression of antisense constructs or DNA fragmentation leads to apoptotic cells death, overview Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.154 additional information Homo sapiens isozyme PI3K-C2alpha is a crucial survival factor for the cell ?
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.154 Homo sapiens O00443 class II PI3K, alpha-isoform
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.154 additional information isozyme PI3K-C2alpha is a crucial survival factor for the cell Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.154 class II phosphoinositide 3-kinase
-
Homo sapiens
2.7.1.154 class II PI3K
-
Homo sapiens
2.7.1.154 PI3K-C2alpha
-
Homo sapiens