EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.4.14 | Escherichia coli | - |
- |
- |
1.8.4.14 | Escherichia coli MC1061 | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
1.8.4.14 | partial | Escherichia coli |
1.8.4.14 | partially purified by (NH4)2SO4 precipitation (30-60% saturation) from MsrA/MsrB double mutants | Escherichia coli |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.8.4.14 | L-methionine (R)-sulfoxide + thioredoxin | - |
Escherichia coli | L-methionine + thioredoxin disulfide + H2O | - |
? | |
1.8.4.14 | L-methionine (R)-sulfoxide + thioredoxin | - |
Escherichia coli MC1061 | L-methionine + thioredoxin disulfide + H2O | - |
? | |
1.8.4.14 | L-methionine + thioredoxin disulfide + H2O | enzyme specific for free L-methionine-(R)-sulfoxide and not met-R-(o) in peptide linkage | Escherichia coli | L-methionine (R)-S-oxide + thioredoxin | - |
? | |
1.8.4.14 | L-methionine + thioredoxin disulfide + H2O | enzyme specific for free L-methionine-(R)-sulfoxide and not met-R-(o) in peptide linkage | Escherichia coli MC1061 | L-methionine (R)-S-oxide + thioredoxin | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.4.14 | fRMsr | - |
Escherichia coli |
1.8.4.14 | methionine sulfoxide reductase | - |
Escherichia coli |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.8.4.14 | dithiothreitol | DTT can replace NADPH, but is much less effective | Escherichia coli | |
1.8.4.14 | NADPH | absolute requirement | Escherichia coli | |
1.8.4.14 | thioredoxin | omission results in a 70% drop in activity | Escherichia coli |