Literature summary extracted from

Wang, L.; Liu, S.; Quarles, L.D.; Spurney, R.F.
Targeted overexpression of G protein-coupled receptor kinase-2 in osteoblasts promotes bone loss (2005), Am. J. Physiol., 288, E826-834.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.7.11.15	functional GRK2 overexpression in transgenic mice, tissue-specific transgenic mRNA expression analysis, tissue-specific overexpression of GRK2 in mouse osteoblasts by usage of the osteocalcin gene-2 promoter	Bos taurus

Protein Variants

EC Number	Protein Variants	Comment	Organism
2.7.11.15	additional information	targeted tissue-specific overexpression of GRK2 in mouse osteoblasts attenuates parathyroid hormone receptor PTH signaling, and promotes bone loss with decreased osteoclastic activity and decreased osteoblasts and trabecular bone, equal effects in female and male mice, overview	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.11.15	Bos taurus	-	-	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.11.15	G protein-coupled receptor kinase-2	-	Bos taurus
2.7.11.15	GRK2	-	Bos taurus

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Release 2023.1 (January 2023)