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Literature summary extracted from

  • Menniti, M.; Iuliano, R.; Amato, R.; Boito, R.; Corea, M.; Le Pera, I.; Gulletta, E.; Fuiano, G.; Perrotti, N.
    Serum and glucocorticoid-regulated kinase Sgk1 inhibits insulin-dependent activation of phosphomannomutase 2 in transfected COS-7 cells (2005), Am. J. Physiol., 288, C148-155.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
5.4.2.8 Insulin incubation with insulin for 45min led to a more than twofold activation of the enzyme Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.4.2.8 serum- and glucocorticoid-regulated kinase Sgk1 decreases the enzymatic activity of PMM2 in the basal state and upon insulin stimulation in intact COS-7 cells Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.4.2.8 cytoplasm expression in COS-7 cells Homo sapiens 5737
-

Organism

EC Number Organism UniProt Comment Textmining
5.4.2.8 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.2.8 D-mannose-1-phosphate
-
 Homo sapiens mannose-6-phosphate
-
 r

Synonyms

EC Number Synonyms Comment Organism
5.4.2.8 PMM2
-
 Homo sapiens