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Literature summary extracted from

  • Nakamura, M.; Mamino, M.; Masaki, M.; Maki, S.; Matsui, R.; Kojima, S.; Hirano, T.; Ohmiya, Y.; Niwa, H.
    Bioluminescence activity of Latia luciferin analogues: replacement of the 2,6,6-trimethylcyclohexene ring onto the methyl-substituted phenyl groups (2004), Tetrahedron Lett., 46, 53-56.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.14.99.21 (1E)-2-methyl-4-(2-methylphenyl)but-1-en-1-yl formate IC50: 0.460 mM Latia neritoides
1.14.99.21 (1E)-2-methyl-4-phenylbut-1-en-1-yl formate IC50: 6.96 mM Latia neritoides
1.14.99.21 oxyluciferin IC50: 0.436 mM Latia neritoides

Organism

EC Number Organism UniProt Comment Textmining
1.14.99.21 Latia neritoides
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.99.21 (1E)-2-methyl-4-(2,4,5-trimethylphenyl)but-1-en-1-yl formate + reduced electron acceptor + O2
-
Latia neritoides 4-(2,4,5-trimethylphenyl)butane-2-one + CO2 + formate + electron acceptor + H2O + hv
-
?
1.14.99.21 (1E)-4-(2,6-dimethylphenyl)-2-methylbut-1-en-1-yl formate + reduced electron acceptor + O2
-
Latia neritoides 4-(2,6-dimethylphenyl)butane-2-one + CO2 + formate + electron acceptor + H2O + hv
-
?
1.14.99.21 (1E)-4-mesityl-2-methylbut-1-en-1-yl formate + reduced electron acceptor + O2
-
Latia neritoides 4-mesitylbutane-2-one + CO2 + formate + electron acceptor + H2O + hv
-
?
1.14.99.21 Latia luciferin + reduced electron acceptor + O2
-
Latia neritoides oxidized Latia luciferin + CO2 + formate + electron acceptor + H2O + hv
-
?

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
1.14.99.21 0.436
-
IC50: 0.436 mM Latia neritoides oxyluciferin
1.14.99.21 0.46
-
IC50: 0.460 mM Latia neritoides (1E)-2-methyl-4-(2-methylphenyl)but-1-en-1-yl formate
1.14.99.21 6.96
-
IC50: 6.96 mM Latia neritoides (1E)-2-methyl-4-phenylbut-1-en-1-yl formate