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Literature summary extracted from

  • Kai, S.; Goto, S.; Tahara, K.; Sasaki, A.; Tone, S.; Kitano, S.
    Indolamine 2,3-dioxygenase is necessary for cytolytic activity of natural killer cells (2004), Scand. J. Immunol., 59, 177-182.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.13.11.52 gamma-interferon activates expression of IDO Homo sapiens

Application

EC Number Application Comment Organism
1.13.11.52 medicine inhibits T-cell activation and proliferation Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.52 1-methyl-DL-tryptophan
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.13.11.52 L-tryptophan + O2 Homo sapiens
-
 N-formyl-L-kynurenine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.52 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.52 B-lymphocyte
-
 Homo sapiens
-
1.13.11.52 additional information T-lymphocyte Homo sapiens
-
1.13.11.52 natural killer cell
-
 Homo sapiens
-
1.13.11.52 peripheral blood mononuclear cell K562 from human erythroleukemia, human hepatocellular carcinoma cell line HepG2 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.52 L-tryptophan + O2
-
 Homo sapiens N-formyl-L-kynurenine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.13.11.52 IDO
-
 Homo sapiens