Literature summary extracted from

Huang, J.K.; Tsai, S.; Huang, G.H.; Gowda, P.G.; Walzer, A.M.; Wen, L.
Higher activity of recombinant bovine deoxyhypusine synthase vs. human deoxyhypusine synthase (2004), Protein Expr. Purif., 35, 32-38.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.5.1.46	subcloning of bovine and human DHS gene, overexpression in Escherichia coli	Homo sapiens
2.5.1.46	subcloning of bovine and human DHS gene, overexpression in Escherichia coli	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.46	Bos taurus	Q6EWQ6	recombinant enzyme	-
2.5.1.46	Homo sapiens	-	recombinant enzyme	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.46	[eIF5A-precursor]-lysine + spermidine	bovine enzyme is approximately 26times as effective as the human enzyme in catalyzing the reaction	Homo sapiens	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	-	?
2.5.1.46	[eIF5A-precursor]-lysine + spermidine	bovine enzyme is approximately 26times as effective as the human enzyme in catalyzing the reaction	Bos taurus	[eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)