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Literature summary extracted from

  • Sakamoto, T.; Miura, K.; Itoh, H.; Tatsumi, T.; Ueguchi-Tanaka, M.; Ishiyama, K.; Kobayashi, M.; Agrawal, G.K.; Takeda, S.; Abe, K.; Miyao, A.; Hirochika, H.; Kitano, H.; Ashikari, M.; Matsuoka, M.
    An overview of gibberellin metabolism enzyme genes and their related mutants in rice (2004), Plant Physiol., 134, 1642-1653.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.2.3.19 additional information expression of KS4, KS7, and KS8 is induced by elicitor treatment Oryza sativa

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.2.3.19 DNA and amino acid sequence determination of genes KS1-9, chromosomal localizations, gene KS9 is a pseudogene, phylogenetic analysis, overview Oryza sativa

Protein Variants

EC Number Protein Variants Comment Organism
4.2.3.19 additional information construction of transgenic rice mutants expressing mutated KS-like genes, the mutant plants show reduced enzyme activity, phenotype analysis and effects on gibberellin metabolism, overview Oryza sativa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.14.14.86 membrane membrane associated Oryza sativa 16020
-
1.14.14.107 membrane
-
 Oryza sativa 16020
-
4.2.3.19 plastid
-
 Oryza sativa 9536
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.86 ent-kaur-16-ene + [reduced NADPH-hemoprotein reductase] + O2 Oryza sativa
-
 ent-kaur-16-en-19-ol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.86 ent-kaur-16-ene-19-al + [reduced NADPH-hemoprotein reductase] + O2 Oryza sativa
-
 ent-kaur-16-en-19-oic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.86 ent-kaur-16-ene-19-ol + [reduced NADPH-hemoprotein reductase] + O2 Oryza sativa
-
 ent-kaur-16-en-19-al + [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
 ?
1.14.14.107 ent-7alpha-hydroxykaur-16-en-19-oate + [reduced NADPH-hemoprotein reductase] + O2 Oryza sativa
-
 gibberellin A12 aldehyde + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.107 ent-kaur-16-en-19-oate + [reduced NADPH-hemoprotein reductase] + O2 Oryza sativa
-
 ent-7alpha-hydroxykaur-16-en-19-oate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.107 gibberellin A12 aldehyde + [reduced NADPH-hemoprotein reductase] + O2 Oryza sativa
-
 gibberellin A12 + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
4.2.3.19 ent-copalyl diphosphate Oryza sativa the enzyme is involved in gibberellin metabolism and biosynthesis of diterpene phytoalexins, overview ent-kaurene + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.86 Oryza sativa
-
-
-
1.14.14.107 Oryza sativa
-
-
-
4.2.3.19 Oryza sativa
-
 multiple ent-kaurene synthase-like, KS-like, genes KS1-9
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.86 leaf sheat Oryza sativa
-
1.14.14.86 panicle
-
 Oryza sativa
-
1.14.14.86 root
-
 Oryza sativa
-
1.14.14.86 stem
-
 Oryza sativa
-
1.14.14.107 leaf
-
 Oryza sativa
-
1.14.14.107 root
-
 Oryza sativa
-
1.14.14.107 shoot
-
 Oryza sativa
-
1.14.14.107 stem
-
 Oryza sativa
-
4.2.3.19 seedling
-
 Oryza sativa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.86 ent-kaur-16-ene + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryza sativa ent-kaur-16-en-19-ol + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.86 ent-kaur-16-ene-19-al + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryza sativa ent-kaur-16-en-19-oic acid + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.86 ent-kaur-16-ene-19-ol + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryza sativa ent-kaur-16-en-19-al + [oxidized NADPH-hemoprotein reductase] + 2 H2O
-
 ?
1.14.14.107 ent-7alpha-hydroxykaur-16-en-19-oate + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryza sativa gibberellin A12 aldehyde + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.107 ent-kaur-16-en-19-oate + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryza sativa ent-7alpha-hydroxykaur-16-en-19-oate + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
1.14.14.107 gibberellin A12 aldehyde + [reduced NADPH-hemoprotein reductase] + O2
-
 Oryza sativa gibberellin A12 + [oxidized NADPH-hemoprotein reductase] + H2O
-
 ?
4.2.3.19 ent-copalyl diphosphate
-
 Oryza sativa ent-kaurene + diphosphate
-
 ?
4.2.3.19 ent-copalyl diphosphate the enzyme is involved in gibberellin metabolism and biosynthesis of diterpene phytoalexins, overview Oryza sativa ent-kaurene + diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.86 OsKO
-
 Oryza sativa
1.14.14.107 OsKAO
-
 Oryza sativa
4.2.3.19 KS
-
 Oryza sativa

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.107 cytochrome P450
-
 Oryza sativa