EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.13.11.34 | (-)-epicatechin | - |
Homo sapiens | |
1.13.11.34 | 11alpha,13-dihydrohelenalin acetate | enzyme from polymorphonuclear leukocyte | Homo sapiens | |
1.13.11.34 | 2,3,4',5-tetrahydroxystilbene-2-O-D-glucoside | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | 4-methylesculetin | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | beta-hydroxyacteoside | enzyme from polymorphonuclear leukocyte | Homo sapiens | |
1.13.11.34 | capsaicin | enzyme from polymorphonuclear leukocyte | Homo sapiens | |
1.13.11.34 | daphnetin | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | esculetin | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | falcarindiol | - |
Sus scrofa | |
1.13.11.34 | forsythiaside | enzyme from polymorphonuclear leukocyte | Homo sapiens | |
1.13.11.34 | forsythiaside | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | fraxetin | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | gingerdione | enzyme from polymorphonuclear leukocyte | Homo sapiens | |
1.13.11.34 | helenalin | enzyme from polymorphonuclear leukocyte | Homo sapiens | |
1.13.11.34 | isoriccardin C | - |
Sus scrofa | |
1.13.11.34 | leucocyanidol | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | marchantin A | - |
Sus scrofa | |
1.13.11.34 | marchantin B | - |
Sus scrofa | |
1.13.11.34 | marchantin D | - |
Sus scrofa | |
1.13.11.34 | marchantin E | - |
Sus scrofa | |
1.13.11.34 | additional information | plant extracts with inhibitory activity on arachidonate 5-lipoxygenase, inhibition of the 5-lipoxygenase pathway is considered to be interesting in the treatment of a variety of inflammatory diseases | Bos taurus | |
1.13.11.34 | additional information | plant extracts with inhibitory activity on arachidonate 5-lipoxygenase, inhibition of the 5-lipoxygenase pathway is considered to be interesting in the treatment of a variety of inflammatory diseases. | Cavia porcellus | |
1.13.11.34 | additional information | plant extracts with inhibitory activity on arachidonate 5-lipoxygenase, inhibition of the 5-lipoxygenase pathway is considered to be interesting in the treatment of a variety of inflammatory diseases. | Glycine max | |
1.13.11.34 | additional information | plant extracts with inhibitory activity on arachidonate 5-lipoxygenase, inhibition of the 5-lipoxygenase pathway is considered to be interesting in the treatment of a variety of inflammatory diseases. | Helianthus tuberosus | |
1.13.11.34 | additional information | plant extracts with inhibitory activity on arachidonate 5-lipoxygenase, inhibition of the 5-lipoxygenase pathway is considered to be interesting in the treatment of a variety of inflammatory diseases. | Mus musculus | |
1.13.11.34 | additional information | plant extracts with inhibitory activity on arachidonate 5-lipoxygenase, inhibition of the 5-lipoxygenase pathway is considered to be interesting in the treatment of a variety of inflammatory diseases. | Rattus norvegicus | |
1.13.11.34 | additional information | plant extracts with inhibitory activity on arachidonate 5-lipoxygenase, inhibition of the 5-lipoxygenase pathway is considered to be interesting in the treatment of a variety of inflammatory diseases. | Sus scrofa | |
1.13.11.34 | myrtol | enzyme from RBL-1 cell | Rattus norvegicus | |
1.13.11.34 | oroxindin | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | paleatin B | - |
Sus scrofa | |
1.13.11.34 | panaxynol | - |
Sus scrofa | |
1.13.11.34 | perrottetin D | - |
Sus scrofa | |
1.13.11.34 | piceid | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | quercetagetin-7-O-beta-D-glucoside | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | radulanin H | - |
Sus scrofa | |
1.13.11.34 | resveratrol | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | shogaol | enzyme from polymorphonuclear leukocyte | Homo sapiens | |
1.13.11.34 | sideritoflavone | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | suspensaside | enzyme from polymorphonuclear leukocyte | Homo sapiens | |
1.13.11.34 | suspensaside | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | tambuletin | polymorphonuclear leukocyte | Rattus norvegicus | |
1.13.11.34 | verbascoside | enzyme from polymorphonuclear leukocyte | Homo sapiens | |
1.13.11.34 | verbascoside | polymorphonuclear leukocyte | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.13.11.34 | additional information | Cavia porcellus | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | ? | - |
? | |
1.13.11.34 | additional information | Mus musculus | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | ? | - |
? | |
1.13.11.34 | additional information | Homo sapiens | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | ? | - |
? | |
1.13.11.34 | additional information | Rattus norvegicus | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | ? | - |
? | |
1.13.11.34 | additional information | Sus scrofa | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | ? | - |
? | |
1.13.11.34 | additional information | Bos taurus | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | ? | - |
? | |
1.13.11.34 | additional information | Glycine max | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | ? | - |
? | |
1.13.11.34 | additional information | Helianthus tuberosus | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.13.11.34 | Bos taurus | - |
- |
- |
1.13.11.34 | Cavia porcellus | - |
- |
- |
1.13.11.34 | Glycine max | - |
- |
- |
1.13.11.34 | Helianthus tuberosus | - |
- |
- |
1.13.11.34 | Homo sapiens | - |
- |
- |
1.13.11.34 | Mus musculus | - |
- |
- |
1.13.11.34 | Rattus norvegicus | - |
- |
- |
1.13.11.34 | Sus scrofa | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
1.13.11.34 | bone marrow | - |
Homo sapiens | - |
1.13.11.34 | granulocyte | - |
Homo sapiens | - |
1.13.11.34 | leukocyte | - |
Sus scrofa | - |
1.13.11.34 | macrophage | - |
Homo sapiens | - |
1.13.11.34 | mast cell | - |
Rattus norvegicus | - |
1.13.11.34 | neutrophil | - |
Homo sapiens | - |
1.13.11.34 | polymorphonuclear leukocyte | - |
Homo sapiens | - |
1.13.11.34 | polymorphonuclear leukocyte | - |
Rattus norvegicus | - |
1.13.11.34 | polymorphonuclear leukocyte | - |
Bos taurus | - |
1.13.11.34 | polymorphonuclear leukocyte | peritoneal | Cavia porcellus | - |
1.13.11.34 | polymorphonuclear leukocyte | peritoneal | Mus musculus | - |
1.13.11.34 | RBL-1 cell | basophilic leukemia cell | Rattus norvegicus | - |
1.13.11.34 | seedling | - |
Helianthus tuberosus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.13.11.34 | additional information | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | Cavia porcellus | ? | - |
? | |
1.13.11.34 | additional information | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | Mus musculus | ? | - |
? | |
1.13.11.34 | additional information | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | Homo sapiens | ? | - |
? | |
1.13.11.34 | additional information | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | Rattus norvegicus | ? | - |
? | |
1.13.11.34 | additional information | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | Sus scrofa | ? | - |
? | |
1.13.11.34 | additional information | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | Bos taurus | ? | - |
? | |
1.13.11.34 | additional information | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | Glycine max | ? | - |
? | |
1.13.11.34 | additional information | key enzyme in leukotriene biosynthesis, catalyzes the initial steps in the conversion of arachidonic acid to biologically active leukotrienes. Leukotrienes are considered as potent mediators of inflammatory and allergic reactions | Helianthus tuberosus | ? | - |
? |