EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.1 | additional information | Arg-vasopressin and phenylephrine activate the enzyme through the phosphoinositide cascade | Rattus norvegicus | |
2.4.1.1 | protein kinase A | activates the enzyme via phosphorylation, which is induced by dibutyryl cAMP, forskolin, and glucagon | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.1 | Caffeine | - |
Rattus norvegicus | |
2.4.1.1 | CP-91149 | - |
Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.1 | (1,4-alpha-D-glucosyl)n + phosphate | Rattus norvegicus | polysaccharide substrate is glycogen | (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate | - |
? | |
2.4.1.1 | additional information | Rattus norvegicus | increased enzyme activity increases 5-phosphoribosyl-1-diphosphate availability in hepatocyte cultures and vice versa, glycogenolysis is a major contributor to PRPP generation in liver tissue in the basal state | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.1 | Rattus norvegicus | - |
male Wistar rats | - |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
2.4.1.1 | phosphoprotein | phosphorylation and dephosphorylation of the enzyme regulates its activity and is catalyzed by a phosphorylase phosphatase and protein kinase A | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.1 | hepatocyte | - |
Rattus norvegicus | - |
2.4.1.1 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.4.1.1 | (1,4-alpha-D-glucosyl)n + phosphate | polysaccharide substrate is glycogen | Rattus norvegicus | (1,4-alpha-D-glucosyl)n-1 + alpha-D-glucose 1-phosphate | - |
? | |
2.4.1.1 | additional information | increased enzyme activity increases 5-phosphoribosyl-1-diphosphate availability in hepatocyte cultures and vice versa, glycogenolysis is a major contributor to PRPP generation in liver tissue in the basal state | Rattus norvegicus | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.4.1.1 | glycogen phosphorylase | - |
Rattus norvegicus |