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Literature summary extracted from

  • Shibata, N.; Kawarai, T.; Lee, J.H.; Lee, H.S.; Shibata, E.; Sato, C.; Liang, Y.; Duara, R.; Mayeux, R.P.; St George-Hyslop, P.H.; Rogaeva, E.
    Association studies of cholesterol metabolism genes (CH25H, ABCA1 and CH24H) in Alzheimer's disease (2006), Neurosci. Lett., 391, 142-146.
    View publication on PubMed

Application

EC Number Application Comment Organism
1.14.99.38 medicine genetic variability in the set of cholesterol metabolism genes: cholesterol 25-hydroxylase, cholesterol 24-hydroxylase and ATP-binding cassette transporter A1 does not influence the development of Alzheimer‘s disease Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.14.14.25 DNA and amino acid sequence determnination and analysis, determination of single nucleotide polymorphisms in North American Caucasians and Caribbean Hispanic Alzheimer patients, overview Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
1.14.14.25 additional information determination of single nucleotide polymorphisms in North American Caucasians and Caribbean Hispanic Alzheimer patients, overview Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.25 additional information Homo sapiens cholesterol metabolism is important in Alzheimer's disease pathogenesis, the enzyme is a risk factor for Alzheimer's disease, along with cholesterol 25-hydroxylase and ATP-binding cassette transporter A1, overview ?
-
 ?
1.14.99.38 cholesterol + AH2 + O2 Homo sapiens genetic variability in the set of cholesterol metabolism genes: cholesterol 25-hydroxylase, cholesterol 24-hydroxylase and ATP-binding cassette transporter A1 does not influence the development of Alzheimer‘s disease 25-hydroxycholesterol + A + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.25 Homo sapiens
-
-
-
1.14.99.38 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.25 additional information cholesterol metabolism is important in Alzheimer's disease pathogenesis, the enzyme is a risk factor for Alzheimer's disease, along with cholesterol 25-hydroxylase and ATP-binding cassette transporter A1, overview Homo sapiens ?
-
 ?
1.14.99.38 cholesterol + AH2 + O2 genetic variability in the set of cholesterol metabolism genes: cholesterol 25-hydroxylase, cholesterol 24-hydroxylase and ATP-binding cassette transporter A1 does not influence the development of Alzheimer‘s disease Homo sapiens 25-hydroxycholesterol + A + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.25 CH24H
-
 Homo sapiens