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Literature summary extracted from

  • Subramanian, A.; Teixeira, J.; Wang, J.; Gil, G.
    A STAT factor mediates the sexually dimorphic regulation of hepatic cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase gene expression by growth hormone (1995), Mol. Cell. Biol., 15, 4672-4682.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.138 lithocholate + [reduced NADPH-hemoprotein reductase] + O2 Mesocricetus auratus a STAT factor mediates the sexually dimorphic regulation of hepatic cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase gene expression by growth hormone 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O
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 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.138 Mesocricetus auratus
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 expressed only in male
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.14.14.138 liver
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 Mesocricetus auratus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.138 lithocholate + [reduced NADPH-hemoprotein reductase] + O2 a STAT factor mediates the sexually dimorphic regulation of hepatic cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase gene expression by growth hormone Mesocricetus auratus 6beta-hydroxylithocholate + [oxidized NADPH-hemoprotein reductase] + H2O
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 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.138 cytochrome P450 3A10/lithocholic acid 6beta-hydroxylase
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 Mesocricetus auratus

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.138 cytochrome P-450
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 Mesocricetus auratus