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Literature summary extracted from

  • Kelleher, D.J.; Karaoglu, D.; Mandon, E.C.; Gilmore, R.
    Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties (2003), Mol. Cell, 12, 101-111.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.99.18 microsome
-
 Canis lupus familiaris
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.4.99.18 Canis lupus familiaris
-
-
-
2.4.99.18 Homo sapiens
-
-
-
2.4.99.18 Mus musculus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.99.18 glycoprotein subunits STT3-A and STT3-B are both glycosylated Canis lupus familiaris

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.99.18 CH12.LX cell lymphoma cell line CH12-LX Mus musculus
-
2.4.99.18 pancreas
-
 Canis lupus familiaris
-
2.4.99.18 skin fibroblast
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.99.18 Glc3Man9GlcNAc2 dolichyl diphosphate + protein L-asparagine
-
 Canis lupus familiaris ?
-
 ?
2.4.99.18 Man9GlcNAc2PP dolichyl diphosphate + protein L-asparagine
-
 Canis lupus familiaris ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.4.99.18 More subunit STT3-A and SST3-B are both expressed in lymphoma cell line CH12-LX Mus musculus
2.4.99.18 More subunit STT3-A and SST3-B are both expressed in skin fibroblasts Homo sapiens
2.4.99.18 More subunit STT3-A is only recovered in the OST-III peak, while STT3-B subunit coelutes with OST-I and OST-II. Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties. OST isoforms that incorporate STT3-B as a subunit are substantially more active and show a reduced ability to discriminate between donor substrates with different oligosaccharide structures Canis lupus familiaris

Synonyms

EC Number Synonyms Comment Organism
2.4.99.18 oligosaccharyltransferase
-
 Mus musculus
2.4.99.18 oligosaccharyltransferase
-
 Homo sapiens
2.4.99.18 oligosaccharyltransferase
-
 Canis lupus familiaris
2.4.99.18 OST-I
-
 Canis lupus familiaris
2.4.99.18 OST-II
-
 Canis lupus familiaris
2.4.99.18 OST-III
-
 Canis lupus familiaris