Literature summary extracted from

Kramer, K.; Harrington, E.O.; Lu, Q.; Bellas, R.; Newton, J.; Sheahan, K.L.; Rounds, S.
Isoprenylcysteine carboxyl methyltransferase activity modulates endothelial cell apoptosis (2003), Mol. Biol. Cell, 14, 848-857.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.1.1.100	additional information	Bos taurus	overexpression of the enzyme may protect against endothelial cell apoptosis by enhancing, the carboxyl methylation posttranslational modification, activity, and subsequent intracellular signalling pathway of Ras GTPase	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.1.100	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.1.100	endothelial cell	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.1.100	additional information	overexpression of the enzyme may protect against endothelial cell apoptosis by enhancing, the carboxyl methylation posttranslational modification, activity, and subsequent intracellular signalling pathway of Ras GTPase	Bos taurus	?	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.1.100	Icmt	-	Bos taurus
2.1.1.100	isoprenylcysteine carboxyl methyltransferase	-	Bos taurus

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Release 2023.1 (January 2023)