EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.6 | Hg2+ | noncompetitive with respect to choline, IC50: 0.0004 mM, mixed type inhibition with respect to acetyl-CoA, IC50: 0.0025 mM, activity can be recovered using 2,3-dimercapto-propanol | Electrophorus electricus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.6 | acetyl-CoA + choline | Electrophorus electricus | synthesis of the neurotransmitter acetylcholine | acetylcholine + CoA | - |
r |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.6 | Electrophorus electricus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.6 | electric organ | - |
Electrophorus electricus | - |
2.3.1.6 | electrocyte | - |
Electrophorus electricus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.6 | acetyl-CoA + choline | - |
Electrophorus electricus | acetylcholine + CoA | - |
r | |
2.3.1.6 | acetyl-CoA + choline | synthesis of the neurotransmitter acetylcholine | Electrophorus electricus | acetylcholine + CoA | - |
r |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.6 | 0.0005 | - |
Hg2+ | pH 7.4, 37°C | Electrophorus electricus |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.3.1.6 | 0.0025 | - |
noncompetitive with respect to choline, IC50: 0.0004 mM, mixed type inhibition with respect to acetyl-CoA, IC50: 0.0025 mM, activity can be recovered using 2,3-dimercapto-propanol | Electrophorus electricus | Hg2+ |