Literature summary extracted from

Hirano, T.; Gong, Y.; Yoshida, K.; Kato, Y.; Yashima, K.; Maeda, M.; Nakagawa, A.; Fujioka, K.; Ohira, T.; Ikeda, N.; Ebihara, Y.; Auer, G.; Kato, H.
Usefulness of TA02 (napsin A) to distinguish primary lung adenocarcinoma from metastatic lung adenocarcinoma (2003), Lung Cancer, 41, 155-162.

Application

EC Number	Application	Comment	Organism
3.4.23.B1	medicine	enzyme is a specific marker in diagnosis of primary lung adenocarcinoma and to distinguish it from metastatic adenocarcinoma	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.4.23.B1	polypeptide + H2O	Homo sapiens	-	peptides	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.23.B1	Homo sapiens	O96009	-	-

Reaction

EC Number	Reaction	Comment	Organism	Reaction ID
3.4.23.B1	proteolytic cleavage of polypeptides to large and stable peptides	belongs to the aspartic proteinases	Homo sapiens	a

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.23.B1	lung adenocarcinoma cell	primary lung adenocarcinoma	Homo sapiens	-
3.4.23.B1	renal proximal tubule	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.23.B1	polypeptide + H2O	-	Homo sapiens	peptides	-	?

pI Value

EC Number	Organism	Comment	pI Value Maximum	pI Value
3.4.23.B1	Homo sapiens	-	-	5.29

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Release 2023.1 (January 2023)