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Literature summary extracted from
- Molecular cloning and expression of guinea pig cytochrome P450c21 cDNA (steroid 21-hydroxylase) isolated from the adrenals (2003), J. Steroid Biochem. Mol. Biol., 86, 123-132.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.14.14.16 | - |
Cavia porcellus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.14.16 | Cavia porcellus | - |
expression in human embryonic kidney 293 cells | - |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.14.16 | adrenal gland | sole source of enzyme expression | Cavia porcellus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.14.16 | 17alpha-hydroxy-progesterone + NADH + O2 | preferred substrate | Cavia porcellus | 17alpha-hydroxy-11-deoxy-corticosterone + NAD+ + H2O | - |
? |  |
| 1.14.14.16 | progesterone + NADH + O2 | - |
Cavia porcellus | deoxycorticosterone + NAD+ + H2O | - |
? | |
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Release 2023.1 (January 2023)
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