EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
2.7.2.8 | D162E | about 0.1% of wild-type activity | Escherichia coli |
2.7.2.8 | K8R | substantial although diminished activity | Escherichia coli |
2.7.2.8 | N158K | substantial although diminished activity | Escherichia coli |
2.7.2.8 | R66K | substantial although diminished activity | Escherichia coli |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.2.8 | ATP | - |
Escherichia coli |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.2.8 | 0.2 | - |
N-acetyl-L-glutamate | wild-type, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 0.29 | - |
ATP | wild-type, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 0.37 | - |
N-acetyl-L-glutamate | mutant D162E, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 0.46 | - |
ATP | mutant D162E, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 2.3 | - |
N-acetyl-L-glutamate | mutant K8R, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 3.3 | - |
ATP | mutant K8R, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 5.2 | - |
ATP | mutant R66K, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 7.9 | - |
ATP | mutant N158Q, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 600 | - |
N-acetyl-L-glutamate | mutant N158Q, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 898 | - |
N-acetyl-L-glutamate | mutant R66K, pH 7.0, 25°C | Escherichia coli |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.2.8 | Escherichia coli | P0A6C8 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.2.8 | ATP + N-acetyl-L-glutamate | - |
Escherichia coli | ADP + N-acetyl-L-glutamate 5-phosphate | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.2.8 | 30.4 | - |
ATP | wild-type, pH 7.0, 25°C | Escherichia coli | |
2.7.2.8 | 41.5 | - |
ATP | mutant N158Q, pH 7.0, 25°C | Escherichia coli |