Literature summary extracted from

Rosenberg, S.H.; Spina, K.P.; Woods, K.W.; Polakowski, J.; Martin, D.L.
Studies directed toward the design of orally active renin inhibitors. 1.Somer factors influencing the absorbtion of small peptides (1993), J. Med. Chem., 36, 449-459.

Application

EC Number	Application	Comment	Organism
3.5.1.14	synthesis	production of L-3-(4-thiazolyl)alanine and D-N-acetyl-D-3-(4-thiazolyl)alanine, which are used as a component of antihypertensive inhibitors of the enzyme renin	Aspergillus niger

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.5.1.14	Aspergillus niger	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.5.1.14	DL-N-acetyl-D,L-3-(4-thiazolyl)alanine + H2O	-	Aspergillus niger	L-3-(4-thiazolyl)alanine + D-N-acetyl-D-3-(4-thiazolyl)alanine	-	?

pH Optimum

EC Number	pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
3.5.1.14	7	-	-	Aspergillus niger

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Release 2023.1 (January 2023)