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Literature summary extracted from

  • le Quere, V.; Plee-Gautier, E.; Potin, P.; Madec, S.; Salaun, J.P.
    Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides (2004), J. Lipid Res., 45, 1446-1458.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.14.14.94 0.0063
-
 Z9(10)-epoxyoctadecanoic acid 37°C, CYP4F3A Homo sapiens
1.14.14.94 0.0261
-
 Z9(10)-epoxyoctadecanoic acid 37°C, CYP4F2 Homo sapiens
1.14.14.94 0.0357
-
 Z9(10)-epoxyoctadecanoic acid 37°C, CYP4F3B Homo sapiens
1.14.14.94 0.0466
-
 Z9(10)-epoxyoctadec-Z12-enoic acid 37°C, CYP4F3A Homo sapiens
1.14.14.94 0.0618
-
 Z12(13)-epoxyoctadec-Z9-enoic acid 37°C, CYP4F3A Homo sapiens
1.14.14.94 0.1006
-
 Z12(13)-epoxyoctadec-Z9-enoic acid 37°C, CYP4F3B Homo sapiens
1.14.14.94 0.1081
-
 Z9(10)-epoxyoctadec-Z12-enoic acid 37°C, CYP4F3B Homo sapiens
1.14.14.94 0.135
-
 Z12(13)-epoxyoctadec-Z9-enoic acid 37°C, CYP4F2 Homo sapiens
1.14.14.94 0.1631
-
 Z9(10)-epoxyoctadec-Z12-enoic acid 37°C, CYP4F2 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.94 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.94 (Z12(13))-epoxyoctadec-(Z9)-enoic acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens ?
-
 ?
1.14.14.94 (Z12(13))-epoxyoctadec-Z9-enoic acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens ?
-
 ?
1.14.14.94 (Z9(10))-epoxyoctadec-(Z12)-enoic acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens ?
-
 ?
1.14.14.94 (Z9(10))-epoxyoctadec-Z12-enoic acid + [reduced NADPH-hemoprotein reductase] + O2
-
 Homo sapiens ?
-
 ?
1.14.14.94 (Z9(10))-epoxyoctadecanoic acid + NADPH + O2 omega-hydroxylation activity and weak (omega-1)-hydroxylation activity Homo sapiens ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.94 CYP4A11
-
 Homo sapiens
1.14.14.94 CYP4F2
-
 Homo sapiens
1.14.14.94 CYP4F3A
-
 Homo sapiens
1.14.14.94 CYP4F3B
-
 Homo sapiens