BRENDA - Enzyme Database show

Changes in trigonelline (N-methylnicotinic acid) content and nicotinic acid metabolism during germination of mungbean (Phaseolus aureus) seeds

Zheng, X.Q.; Hayashibe, E.; Ashihara, H.; J. Exp. Bot. 56, 1615-1623 (2005)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.1.1.7
additional information
nicotinic acid and nicotinamide inhibit the growth of roots
Vigna radiata var. radiata
2.4.2.19
additional information
nicotinic acid and nicotinamide inhibit growth of roots
Vigna radiata var. radiata
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
2.4.2.19
Mg2+
-
Vigna radiata var. radiata
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.7
S-adenosyl-L-methionine + nicotinate
Vigna radiata var. radiata
enzyme is involved in metabolism of nicotinic acid and nicotinamide, trigonelline and pyridine nucleotide pathway overview
S-adenosyl-L-homocysteine + N-methylnicotinate
i.e. trigonelline
-
?
2.4.2.19
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
Vigna radiata var. radiata
synthesis of precursors for trigonelline biosynthesis, feeding experiments, overview
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
?
3.5.1.19
additional information
Vigna radiata var. radiata
changes in trigonelline content and nicotinic acid metabolism during germination, overview
?
-
-
-
3.5.1.19
nicotinamide + H2O
Vigna radiata var. radiata
the enzyme is involved in the trigonelline biosynthesis
nicotinate + NH3
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.1.1.7
Vigna radiata var. radiata
-
i.e. Vigna radiate
-
2.4.2.19
Vigna radiata var. radiata
-
i.e. Vigna radiata
-
3.5.1.19
Vigna radiata var. radiata
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.7
seed
enzyme activity increases in embryonic axes, but decreases in cotyledons during germination
Vigna radiata var. radiata
-
2.1.1.7
seedling
etiolated
Vigna radiata var. radiata
-
2.4.2.19
cotyledon
-
Vigna radiata var. radiata
-
2.4.2.19
embryo
embryonic axes, high enzyme activity
Vigna radiata var. radiata
-
2.4.2.19
additional information
nicotinic acid metabolism and content of trigonelline in different tissues of the seeds and seedlings and during differentiation
Vigna radiata var. radiata
-
2.4.2.19
seed
-
Vigna radiata var. radiata
-
2.4.2.19
seedling
-
Vigna radiata var. radiata
-
3.5.1.19
cotyledon
-
Vigna radiata var. radiata
-
3.5.1.19
embryo
embryonic axis
Vigna radiata var. radiata
-
3.5.1.19
seed
activity during germination, overview
Vigna radiata var. radiata
-
Specific Activity [micromol/min/mg]
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.1.1.7
additional information
-
determination of trigonelline content in vivo in seedlings during germination, overview
Vigna radiata var. radiata
2.1.1.7
0.0000013
-
crude extract of cotyledons
Vigna radiata var. radiata
2.1.1.7
0.0000032
-
crude extract of embryonic axes
Vigna radiata var. radiata
2.4.2.19
additional information
-
-
Vigna radiata var. radiata
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.7
S-adenosyl-L-methionine + nicotinate
-
659608
Vigna radiata var. radiata
S-adenosyl-L-homocysteine + N-methylnicotinate
-
-
-
?
2.1.1.7
S-adenosyl-L-methionine + nicotinate
enzyme is involved in metabolism of nicotinic acid and nicotinamide, trigonelline and pyridine nucleotide pathway overview
659608
Vigna radiata var. radiata
S-adenosyl-L-homocysteine + N-methylnicotinate
i.e. trigonelline
-
-
?
2.4.2.19
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
synthesis of precursors for trigonelline biosynthesis, feeding experiments, overview
659608
Vigna radiata var. radiata
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
2.4.2.19
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
direct conversion of quinolinic acid to nicotinic acid mononucleotide
659608
Vigna radiata var. radiata
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
3.5.1.19
additional information
changes in trigonelline content and nicotinic acid metabolism during germination, overview
659608
Vigna radiata var. radiata
?
-
-
-
-
3.5.1.19
nicotinamide + H2O
the enzyme is involved in the trigonelline biosynthesis
659608
Vigna radiata var. radiata
nicotinate + NH3
-
-
-
?
3.5.1.19
nicotinamide + H2O
assay with radiolabeled substrate
659608
Vigna radiata var. radiata
nicotinate + NH3
-
-
-
?
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.1.1.7
30
-
assay at
Vigna radiata var. radiata
2.4.2.19
30
-
assay at
Vigna radiata var. radiata
3.5.1.19
30
-
assay at
Vigna radiata var. radiata
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.1.1.7
7.6
-
assay at
Vigna radiata var. radiata
2.4.2.19
7.6
-
assay at
Vigna radiata var. radiata
3.5.1.19
7.6
-
assay at
Vigna radiata var. radiata
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.1.1.7
additional information
nicotinic acid and nicotinamide inhibit the growth of roots
Vigna radiata var. radiata
2.4.2.19
additional information
nicotinic acid and nicotinamide inhibit growth of roots
Vigna radiata var. radiata
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
2.4.2.19
Mg2+
-
Vigna radiata var. radiata
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.7
S-adenosyl-L-methionine + nicotinate
Vigna radiata var. radiata
enzyme is involved in metabolism of nicotinic acid and nicotinamide, trigonelline and pyridine nucleotide pathway overview
S-adenosyl-L-homocysteine + N-methylnicotinate
i.e. trigonelline
-
?
2.4.2.19
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
Vigna radiata var. radiata
synthesis of precursors for trigonelline biosynthesis, feeding experiments, overview
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
?
3.5.1.19
additional information
Vigna radiata var. radiata
changes in trigonelline content and nicotinic acid metabolism during germination, overview
?
-
-
-
3.5.1.19
nicotinamide + H2O
Vigna radiata var. radiata
the enzyme is involved in the trigonelline biosynthesis
nicotinate + NH3
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.7
seed
enzyme activity increases in embryonic axes, but decreases in cotyledons during germination
Vigna radiata var. radiata
-
2.1.1.7
seedling
etiolated
Vigna radiata var. radiata
-
2.4.2.19
cotyledon
-
Vigna radiata var. radiata
-
2.4.2.19
embryo
embryonic axes, high enzyme activity
Vigna radiata var. radiata
-
2.4.2.19
additional information
nicotinic acid metabolism and content of trigonelline in different tissues of the seeds and seedlings and during differentiation
Vigna radiata var. radiata
-
2.4.2.19
seed
-
Vigna radiata var. radiata
-
2.4.2.19
seedling
-
Vigna radiata var. radiata
-
3.5.1.19
cotyledon
-
Vigna radiata var. radiata
-
3.5.1.19
embryo
embryonic axis
Vigna radiata var. radiata
-
3.5.1.19
seed
activity during germination, overview
Vigna radiata var. radiata
-
Specific Activity [micromol/min/mg] (protein specific)
EC Number
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
2.1.1.7
additional information
-
determination of trigonelline content in vivo in seedlings during germination, overview
Vigna radiata var. radiata
2.1.1.7
0.0000013
-
crude extract of cotyledons
Vigna radiata var. radiata
2.1.1.7
0.0000032
-
crude extract of embryonic axes
Vigna radiata var. radiata
2.4.2.19
additional information
-
-
Vigna radiata var. radiata
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.7
S-adenosyl-L-methionine + nicotinate
-
659608
Vigna radiata var. radiata
S-adenosyl-L-homocysteine + N-methylnicotinate
-
-
-
?
2.1.1.7
S-adenosyl-L-methionine + nicotinate
enzyme is involved in metabolism of nicotinic acid and nicotinamide, trigonelline and pyridine nucleotide pathway overview
659608
Vigna radiata var. radiata
S-adenosyl-L-homocysteine + N-methylnicotinate
i.e. trigonelline
-
-
?
2.4.2.19
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
synthesis of precursors for trigonelline biosynthesis, feeding experiments, overview
659608
Vigna radiata var. radiata
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
2.4.2.19
pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate
direct conversion of quinolinic acid to nicotinic acid mononucleotide
659608
Vigna radiata var. radiata
nicotinate D-ribonucleotide + diphosphate + CO2
-
-
-
?
3.5.1.19
additional information
changes in trigonelline content and nicotinic acid metabolism during germination, overview
659608
Vigna radiata var. radiata
?
-
-
-
-
3.5.1.19
nicotinamide + H2O
the enzyme is involved in the trigonelline biosynthesis
659608
Vigna radiata var. radiata
nicotinate + NH3
-
-
-
?
3.5.1.19
nicotinamide + H2O
assay with radiolabeled substrate
659608
Vigna radiata var. radiata
nicotinate + NH3
-
-
-
?
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.1.1.7
30
-
assay at
Vigna radiata var. radiata
2.4.2.19
30
-
assay at
Vigna radiata var. radiata
3.5.1.19
30
-
assay at
Vigna radiata var. radiata
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.1.1.7
7.6
-
assay at
Vigna radiata var. radiata
2.4.2.19
7.6
-
assay at
Vigna radiata var. radiata
3.5.1.19
7.6
-
assay at
Vigna radiata var. radiata